| Description |
1 online resource : illustrations |
| Series |
Translational epigenetics series |
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Translational epigenetics series.
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| Contents |
Cover; Title page; Copyright page; Contents; List of Contributors; Preface; Section I -- Neuropsychiatric disorders and epigenetics: general aspects; Chapter Introduction to neuropsychiatric disorders and epigenetics; 1.1 -- Introduction; 1.2 -- Neuropsychiatry and Neuropsychiatric Disorders; 1.3 -- Historical Outline of Neuropsychiatric Disorders; 1.4 -- Neuropsychiatric Disorders and Epigenetics; 1.5 -- Epigenetics and Neuropsychiatric Disorders: Translational Aspects; Abbreviation; Glossary; Acknowledgment; References; Chapter Environmental factors and epigenetics of neuropsychiatric disorders |
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2.1 -- Introduction: Gene X Environment Interactions Revisited2.2 -- The Epigenetic Dimension of Neuroplasticity; 2.3 -- What are Molecular Epigenetic Mechanisms?; 2.3.1 -- Epigenetic Tagging of DNA; 2.3.2 -- Epigenetic Tagging of Histones; 2.4 -- ELA as a Major Risk Factor for Neuropsychiatric Disorders; 2.5 -- The Stress System as a Mediator of ELA; 2.6 -- Epigenetic Programming of the Stress System; 2.6.1 -- Epigenetic Programming of the GR by Early Life Experiences; 2.6.2 -- Epigenetic Programming of Fkbp5 by Glucocorticoids and ELA; 2.7 -- Epigenetic Programming of Hypothalamic Neuropeptides by ELA |
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2.7.1 -- Epigenetic Programming of Crh2.7.2 -- Epigenetic Programming of Avp by ELA; 2.7.3 -- Epigenetic Programming of Pituitary Pomc by ELA; 2.8 -- Epigenetic Programming of the HPA Axis by Early Nutrition; 2.8.1 -- Epigenetic Programming of the GR by Early Undernutrition; 2.8.2 -- Epigenetic Programming of Hypothalamic Pomc by Early Overnutrition; 2.9 -- Other Epigenetic Aspects of Nutritional Effects on Neuropsychiatric Disorders; 2.10 -- Therapeutic Prospects; Abbreviations; Glossary; Acknowledgment; References; Chapter Epigenetic biomarkers in neuropsychiatric disorders; 3.1 -- Introduction |
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3.2 -- Schizophrenia3.2.1 -- DNA Methylation; 3.2.1.1 -- Gamma-Aminobutyric Acid; 3.2.1.2 -- Reelin; 3.2.1.3 -- Brain-Derived Neurotrophic Factor; 3.2.1.4 -- Sex-Determining Region Y-Box Containing Gene 10; 3.2.1.5 -- Catechol-O-Methyltransferase; 3.2.1.6 -- Genome-Wide Analysis; 3.2.1.7 -- Miscellaneous; 3.2.2 -- Histone Modifications; 3.2.3 -- MicroRNAs; 3.3 -- Bipolar Disorder; 3.3.1 -- DNA Methylation; 3.3.1.1 -- BDNF; 3.3.1.2 -- Serotonin (5HT); 3.3.1.3 -- GABA; 3.3.1.4 -- Human Leukocyte Antigen Complex Group 9 Gene; 3.3.1.5 -- Genome-Wide Analysis; 3.3.1.6 -- Miscellaneous; 3.3.2 -- Histone Modifications |
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3.3.3 -- MicroRNAs3.4 -- Major Depressive Disorder; 3.4.1 -- DNA Methylation; 3.4.1.1 -- BDNF; 3.4.1.2 -- Monoamines; 3.4.1.3 -- Hypothalamic-Pituitary-Adrenal Axis; 3.4.1.4 -- Genome-Wide Analysis; 3.4.1.5 -- Miscellaneous; 3.4.2 -- Histone Modifications; 3.4.3 -- MicroRNAs; 3.5 -- Conclusions; Abbreviations; Glossary; Acknowledgments; References; Section II -- Epigenetics of neuropsychiatric disorders; Chapter Epigenetics and cognitive disorders-translational aspects; 4.1 -- Introduction: Epigenetics and Cognitive Disorders; 4.2 -- DNA Methylation and Histone Tail Modifications |
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4.3 -- Epigenetic Changes in Alzheimer's Disease |
| Notes |
The epigenetics of brain aging and psychiatric disorders Huan Gong, Xiangru Xu 9. Epigenetic therapy may alleviate cognitive deficits in Down syndrome by downregulating overexpressed chromosome 21 gene products Alain D. Dekker, Peter P. De Deyn and Marianne G. Rots 10. Epigenetics and Multiple Sclerosis Lara Kular, Gonçalo Castelo-Branco and Maja Jagodic 11. Epigenetics and Migraine Siew Hua Gan and Munvar Miya Shaik 12. The role of epigenetics in the pathophysiology of epilepsy Sung Min Nam and Kyung-Ok Cho 13. Epigenetic Dysregulation in Brain Tumors and Neurodevelopment Marco M. Hefti and Nadejda Tsankova 14. Epigenetics and Cerebrovascular Diseases Carolina Soriano-Tárraga, Jordi Jiménez-Conde and Jaume Roquer 15. Epigenetics and Eating Disorders Helge Frieling, Vanessa Buchholz 16. Epigenetics in Obesity Brian M. Shewchuk 17. Epigenetics and Drug Addiction-Translational Aspects Jian Feng 18 |
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Epigenetics and Alcohol Use Disorders Sneha Sagarkar and Amul Sakharkar Section III: Summary and Outlook 19. Summary and Outlook Dag H. Yasui, Jacob Peedicayil and Dennis R. Grayson |
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CIP data; item not viewed |
| Subject |
Neurobehavioral disorders -- Genetic aspects
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Epigenetics.
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HEALTH & FITNESS -- Diseases -- General.
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MEDICAL -- Clinical Medicine.
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MEDICAL -- Diseases.
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MEDICAL -- Evidence-Based Medicine.
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MEDICAL -- Internal Medicine.
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Epigenetics
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| Form |
Electronic book
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| Author |
Yasui, Dag, editor
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Peedicayil, Jacob, editor
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Grayson, Dennis Robert, 1953- editor.
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| ISBN |
9780128005279 |
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0128005270 |
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