| Description |
1 online resource (205 pages) |
| Contents |
Preface; Acknowledgments; Contents; 1: Introduction; 1.1 Tinnitus and Tinnitus-Related Distress; References; 2: Stress and Glucocorticoid Action in the Brain and Ear: Implications for Tinnitus; 2.1 Introduction; 2.2 The Concept Stress, Allostasis, and the Allostatic Load; 2.3 Mediators of the Stress Response; 2.4 Pulsatility of the HPA Axis; 2.5 Access of Corticosteroids to Brain Targets; 2.6 Corticosteroid Receptors; 2.7 Behavioral and Neuroendocrine Feedback Action of Corticosteroids in the Brain; 2.8 Role of MR and GR in Coping with Stress; 2.9 MR:GR Balance: Genetics |
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2.10 MR/GR Balance: Phenotype2.11 Implications for Tinnitus; 2.12 Corticosteroids-Based Treatment Options; References; 3: Stress-Related Psychological Disorders and Tinnitus; 3.1 Introduction; 3.2 Psychological Disorders; 3.3 Affective Disorders; 3.4 Anxiety Disorders; 3.5 Type D Personality and Tinnitus; 3.6 Population Studies Reporting Association Between Tinnitus and Stress; 3.7 Does Tinnitus Cause Stress or Does Stress Cause Tinnitus?; 3.8 Proposing Treatments: Enrolment Issues; 3.9 Treatment of Comorbid Psychological Disorders in Patients with Tinnitus; References |
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4: Circadian Influences on the Auditory System4.1 Introduction; 4.2 Circadian Rhythms; 4.2.1 What Are They; 4.2.2 Organization of the Circadian System; 4.3 Molecular Biology of Circadian Rhythms; 4.3.1 Core Clock Genes; 4.3.2 From Molecules to Physiology; 4.3.2.1 The SCN and the Adrenal Glands: Teamwork for Body Synchrony?; 4.3.2.2 Physiological Functions Controlled by Circadian Rhythms and Their Dysregulation; 4.3.3 Auditory System and Circadian Rhythms; 4.3.3.1 The Day-Night Susceptibility to Auditory Trauma |
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4.3.3.2 Involvement of Neurotrophic Signaling in the Differential Sensitivity to Noise Trauma Throughout the Day4.3.3.3 Molecular Biology of Cochlear Circadian Rhythm; 4.3.3.4 Circadian Rhythms in the Inferior Colliculus; 4.3.3.5 Central Influence of Cochlear and IC Rhythms: Predictive Models; 4.3.4 Auditory Pathologies and Disrupted Circadian Rhythms; 4.3.4.1 Psychological Consequences of Disrupted Circadian Rhythms and the Potential Role in Tinnitus; 4.4 Clinical Implications of Circadian Influences for Tinnitus Therapy; References; 5: Animal Models of Stress and Tinnitus; 5.1 Stress |
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5.2 Hypothalamic-Pituitary-Adrenal Axis and the Auditory System5.3 Recognizing Stress in Animals; 5.4 Causing Stress in Animals; 5.4.1 Restraint Stress; 5.4.2 Electric Foot Shock-Induced Stress; 5.4.3 Noise-Induced Stress; 5.5 Stress and the Cochlea; 5.5.1 The HPA Axis Signaling System; 5.5.2 The Local Cochlear CRF-Signaling System; 5.6 Stress and the Central Nervous System; 5.7 Stress and Tinnitus; 5.7.1 Stress Causing Tinnitus; 5.7.2 Tinnitus Causing Stress; 5.8 Recognizing Tinnitus in Animals?; 5.8.1 Using Classical Conditioning; 5.8.2 Using the Gap-Startle Response |
| Summary |
This book provides up-to-date scientific information on the pathways by which psychosocial stress can affect the auditory system and describes current approaches to the management of patients with stress related tinnitus. The latest evidence is presented on aspects such as the role of stress hormones in auditory function, the effects of allostatic load, circadian sensitivity to auditory trauma, and the association between stress-related biomarkers and tinnitus. The clinically oriented chapters discuss psychometric instruments of value in the tinnitus clinic and present stress related tinnitus treatment protocols and outcome measures. It is widely acknowledged that the tinnitus percept acts as a stressor. However, it is also now evident that psychosocial stress can play a causative role in tinnitus and that the impact varies according to the level, duration, and quality of the stress. Assessment of the types and levels of stress in tinnitus patients before, during, and after treatment is therefore very important. Healthcare professionals attending tinnitus patients will benefit from the information that this book provides on the relationship between tinnitus and stress and from the practical guidance that it offers |
| Notes |
5.9 Summary |
| Bibliography |
Includes bibliographical references at the end of each chapters |
| Notes |
Print version record |
| Subject |
Tinnitus.
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Stress (Physiology)
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Biochemical markers.
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Diseases -- Animal models.
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Outcome assessment (Medical care)
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Tinnitus -- etiology
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Tinnitus -- psychology
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Biomarkers
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Disease Models, Animal
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Stress, Psychological -- complications
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Treatment Outcome
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Tinnitus
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MEDICAL -- Anatomy.
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SCIENCE -- Life Sciences -- Human Anatomy & Physiology.
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Outcome assessment (Medical care)
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Diseases -- Animal models
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Biochemical markers
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Stress (Physiology)
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Tinnitus
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| Genre/Form |
Electronic book
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| Form |
Electronic book
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| Author |
Szczepek, Agnieszka J., editor
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Mazurek, Birgit, editor
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| ISBN |
9783319583976 |
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3319583972 |
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9783319863979 |
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3319863975 |
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9783319583983 |
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3319583980 |
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