Title Vitamin D and the lung : mechanisms and disease associations / edited by Augusto A. Litonjua

Published Totowa, N.J. : Humana ; London : Springer [distributor], 2012

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Description 1 online resource : illustrations (some color) Series Respiratory medicine ; 3 Respiratory medicine (New York, N.Y.) ; 3. Contents Part 1. Introduction -- Vitamin D Deficiency: Historical Perspectives / Kumaravel Rajakumar and Michael F. Holick -- Perspective: Evolution of Human Skin Color: How Low Levels of Vitamin D Drove Natural Selection / Scott T. Weiss -- Part 2. Vitamin D Mechanisms of Relevance to Lung Diseases -- Vitamin D and Lung Development in Early Life / Virender K. Rehan and John S. Torday -- Vitamin D and the Innate Immune Response / Aria Vazirnia and Philip T. Liu -- Vitamin D and Regulatory T Cells / Zoë Urry, Sarah Dimeloe and Catherine M. Hawrylowicz -- Dendritic Cell Modulation by the Vitamin D System / Luciano Adorini, Gilles Laverny and Giuseppe Penna -- Vitamin D Modulates Airway Smooth Muscle Function / Audreesh Banerjee and Reynold A. Panettieri Jr. -- Vitamin D: Genetics and Genomic Effects / Kelan G. Tantisira -- Part 3. Disease Associations -- Acute Respiratory Infections / Jonathan M. Mansbach and Carlos A. Camargo Jr. -- The Role of Vitamin D in the Development, Exacerbation, and Severity of Asthma and Allergic Diseases / Augusto A. Litonjua -- Vitamin D and Chronic Obstructive Pulmonary Disease / Wim Janssens, An Lehouck, Marc Decramer and Ghislaine Gayan-Ramirez -- Cystic Fibrosis / Helen M. Buntain and Anne B. Chang -- Tuberculosis / Adrian R. Martineau -- Lung Cancer / David C. Christiani and C. Matthew Kinsey Summary Vitamin D deficiency is a worldwide problem and many associations with diseases are being discovered. Recently, there has been an interest in the role that vitamin D plays in the inception and progression of lung disease. Vitamin D and the Lung: Mechanisms and Disease Associations delivers a concise, evidence-based review of the evidence for a role of vitamin D in various lung disorders. Divided into three sections, the first section of the book delivers a review of how vitamin D deficiency emerged in human populations, and gives a perspective on how humans evolved to maximize the efficiency of production of vitamin D. The second section of the book reviews aspects of vitamin D mechanisms on different immune cells, lung tissue, and genetics that have potential impact on lung disease. The third section follows with chapters on associations of vitamin D with the risk for viral infections, asthma and allergies, chronic obstructive pulmonary disease, cystic fibrosis, tuberculosis, and finally, lung cancer with an emphasis on ongoing research and clinical issues and needs for future research in each field. Written by an international group of expert authors, Vitamin D and the Lung: Mechanisms and Disease Associations is an essential text for researchers in the respiratory field and practicing clinicians including internists, pulmonologists, and primary care personnel Bibliography Includes bibliographical references and index Notes Print version record Subject Lungs -- Diseases -- Etiology Vitamin D deficiency. Vitamin D -- Health aspects Respiratory organs -- Diseases. Respiratory Tract Diseases Vitamin D Deficiency Respiration Disorders MEDICAL -- Pulmonary & Thoracic Medicine. Médecine. Respiratory organs -- Diseases Lungs -- Diseases -- Etiology Vitamin D deficiency Form Electronic book Author Litonjua, Augusto A. ISBN 9781617798887 1617798886

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