| Description |
1 online resource (345 p.) |
| Contents |
Cover -- Half Title -- Title Page -- Copyright Page -- Table of Contents -- Preface -- Acknowledgments -- Author Bio -- 1 Genetic Analysis -- 1.1 Introduction -- 1.2 Monogenic Traits -- 1.3 Linkage Analysis -- 1.3.1 Linkage -- 1.3.2 Linkage Analysis -- 1.3.3 Polymorphic DNA Markers -- 1.4 Linkage Disequilibrium -- 1.4.1 Linkage Disequilibrium at One Pair of Loci -- 1.4.2 Linkage Equilibrium -- 1.4.3 Linkage Disequilibrium at More Than Two Loci -- 1.4.4 Linkage Disequilibrium Within and Between Populations -- 1.4.5 Population Genetics of Linkage Disequilibrium |
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1.4.6 Applications of Linkage Disequilibrium -- 1.4.7 Linkage Disequilibrium and Human Genome -- 1.5 Mendelian Pedigree Patterns -- 1.5.1 Dominance and Recessiveness of Characters -- 1.5.2 Types of Mendelian Pedigree -- 1.6 Mendelian Pedigree Analysis -- 1.6.1 Pedigree Analysis -- 1.6.2 Patterns Indicating a Recessive Trait -- 1.6.2.1 Autosomal Recessive -- 1.6.3 Patterns Indicating a Dominant Trait -- 1.6.3.1 Autosomal Dominant Trait -- 1.6.4 X-Linked Recessive -- 1.6.5 X-Linked Dominant -- 1.6.6 Calculations for the Risk Allele By Pedigree Analysis -- 1.7 Allele Frequency Estimation |
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1.7.1 Determination of Allele Frequency -- 1.7.1.1 DNA Pooling -- 1.8 The Hardy-Weinberg Law -- 1.8.1 Infinitely Large Population -- 1.8.2 Random Mating -- 1.8.3 No Mutation -- 1.8.4 No Immigration -- 1.8.5 No Evolutionary Forces Affecting the Population -- 1.8.6 Conclusion -- 1.8.7 Circumstances in Which the Hardy-Weinberg Law Cannot Apply -- 1.9 Multifactorial Inheritance -- 1.9.1 Open Neural Tube Defects (ONTDs) -- 1.9.2 Hip Dysplasia -- 1.9.3 Height -- 1.9.4 Model for Multifactorial Inheritance -- 1.10 Heritability -- 1.10.1 Types of Heritability |
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1.10.2 Methods of Estimating the Heritability -- 1.10.3 Heritability and the Environmentability of a Trait -- 1.10.4 Misconceptions Or Misunderstandings On Heritability -- 1.10.5 Heritability of Human Height -- 1.10.6 Heritability and Human Behavior -- 1.10.7 Designs for Estimating the Heritability of Behavior -- 1.10.7.1 Twin Studies -- 1.10.7.2 Adoption Studies -- 1.10.7.3 Developmental Models -- 1.10.8 Candidate Genes for Studying Heritability -- 1.11 Polygenic Inheritance -- 1.11.1 Human Skin Colour -- 1.12 Haplotyping -- 1.12.1 The Importance of Haplotype Analysis |
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1.12.2 Methods of Haplotyping -- 1.12.2.1 Haplotyping for Pedigree -- 1.12.2.2 DNA Sample Based Haplotyping Methods -- 1.13 Conclusion -- References -- 2 Genetic Variations in Human Beings -- 2.1 Introduction -- 2.2 The Origin of Human Beings -- 2.2.1 Out of Africa Theory and Supporting Evidence -- 2.2.2 Evidence From Population Genetics -- 2.3 Genetic Diversity Among Human Beings -- 2.3.1 The Salient Features of Human Genetic Diversity -- 2.3.1.1 From Genetic Research -- 2.3.1.2 Findings From Fossil Remains -- 2.3.1.3 Techniques for the Measurement of Genetic Diversity |
| Notes |
Description based upon print version of record |
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2.4 Genetic Polymorphisms |
| Form |
Electronic book
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| ISBN |
9781000824490 |
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1000824497 |
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