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Book Cover
E-book
Author Delves, Peter J

Title Roitt's Essential Immunology
Edition 13th ed
Published Somerset : John Wiley & Sons, Incorporated, 2016

Copies

Description 1 online resource (1340 pages)
Series Essentials Ser
Essentials Ser
Contents 880-01 Title Page; Table of Contents; About the authors; Acknowledgments; Preface; Abbreviations; How to use your textbook; About the companion website; Part 1: Fundamentals of immunology; CHAPTER 1: Innate immunity; Introduction; Knowing when to make an immune response; Pattern recognition receptors detect nonself; Immune responses are tailored towards particular types of infection; Innate versus adaptive immunity; External barriers against infection; Cells of the immune system; The beginnings of an immune response; There are several classes of pattern recognition receptors
880-01/(S What the T-cell seesProcessing of intracellular antigen for presentation by class I MHC; Processing of extracellular antigen for class II MHC presentation follows a different pathway; Cross-presentation of antigens; The nature of the "groovy" peptide; The αβ T-cell receptor binds to a combination of MHC and peptide; T-cell recognition of non-protein antigens; Antigen recognition by γδ T-cells; Superantigens are extremely powerful activators of T-cells; Why do αβ T-cells need to recognize antigen in such a complex way; SUMMARY; FURTHER READING; Chapter 6: The anatomy of the immune response
Phagocytic cells engulf and kill microorganismsPhagocytes employ an array of killing mechanisms; Complement facilitates phagocytosis and bacterial lysis; Humoral mechanisms provide an additional defensive strategy; Natural killer cells kill virally infected cells; Dealing with large parasites; The innate immune system instigates adaptive immunity; SUMMARY; FURTHER READING; CHAPTER 2: Specific acquired immunity; Just to recap ... ; Introduction; Antigens -- "shapes" recognized by the immune system; Antibody -- a specific antigen recognition molecule; Clonal selection; Immunological memory
Antigen specificityVaccination produces acquired memory; Cell-mediated immunity protects against intracellular organisms; Integration of the immune response; Immunopathology; SUMMARY; FURTHER READING; CHAPTER 3: Antibodies; Just to recap ... ; Introduction; The division of labor; Five classes of immunoglobulin; The IgG molecule; The structure and function of the immunoglobulin classes; Genetics of antibody diversity and function; SUMMARY; FURTHER READING; CHAPTER 4: Membrane receptors for antigen; Just to recap ... ; Introduction; The B-cell surface receptor for antigen (BCR)
The T-cell surface receptor for antigen (TCR)The generation of diversity for antigen recognition; Invariant natural killer T-cell receptors bridge innate and adaptive immunity; NK receptors; The major histocompatibility complex (MHC); Pathogen recognition receptors provide the first line of detection for microbial antigen; SUMMARY; FURTHER READING; CHAPTER 5: Antigen-specific recognition; Just to recap ... ; Introduction; What antibodies see; Identifying B-cell epitopes on a protein; Thermodynamics of antibody-antigen interactions; Specificity and cross-reactivity of antibodies
Notes Just to recap ..
Print version record
Subject Immune system.
Immune system
Reading List HMM204 recommended text 2024
Form Electronic book
Author Martin, Seamus J
Burton, Dennis R
Roitt, Ivan M
ISBN 9781118416044
111841604X