Hematopoietic Stem Cells -- The Road to Commitment: Lineage Restriction Events in Hematopoiesis -- Hematopoietic Stem Cell Niches -- Molecular Biology of Erythropoiesis -- Development of Megakaryocytes -- Development of Macrophages and Granulocytes -- Development of T Lymphocytes -- Development of B Lymphocytes -- Development of Natural Killer cells -- Leukemic Stem Cells: New Therapeutic Targets? -- Targeting Signal Transduction Pathways in Hematopoietic Disorders
Summary
Covers molecular basis for hematopoietic stem cell commitment and terminal differentiation. This title discusses various discoveries in role of transcription factors and the influence of cytokines in the context of human and mouse hematopoietic lineages