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E-book

Title Precision approaches to heterogeneity in asthma / Allan R. Brasier, Nizar N. Jarjour, editors
Published Cham, Switzerland : Springer, [2023]

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Description 1 online resource
Series Advances in Experimental Medicine and Biology ; volume 1426
Advances in experimental medicine and biology ; v. 1426.
Contents Intro -- Introduction -- Contents -- Part I: The Spectrum of Asthma Epidemiology -- Epidemiology of Asthma: Prevalence and Burden of Disease -- Introduction to Asthma Epidemiology -- Asthma Surveillance -- Asthma Surveillance Programs -- United States -- Global Surveillance -- The International Study of Asthma and Allergies in Children (ISAAC) -- The European Community Respiratory Health Survey -- The World Health Surveys -- Global Burden of Asthma -- The Global Asthma Report -- Challenges to Asthma Surveillance, Therapy, and Control -- The Heterogeneity of Asthma -- Environmental Exposures
Ethnic and Racial Diversity -- Sexual Dimorphism -- The Burden of Asthma -- Asthma and the COVID-19 Pandemic -- Future Directions: The Role of Digital Health -- Summary -- References -- The Role of Climate Change in Asthma -- Introduction -- Air Pollution -- Wildfires -- Sand and Dust Storms -- Global Warming, Flooding, and Thunderstorms -- Mold Spores -- Pollen -- Health Disparities -- Adaptation and Mitigation -- Clinical Considerations -- Population Health -- Conclusion -- References -- Life Course of Asthma -- Introduction: Time for a Paradigm Shift -- The Prenatal Period and Asthma
Family History of Asthma -- Prenatal Exposure to Tobacco Smoke -- Prenatal Exposure to Pollution -- Prenatal Exposure to Antibiotics -- Prenatal Vitamin D Deficiency -- Prenatal Diet and Asthma -- Prenatal Maternal Obesity and Effects on Their Children -- Prenatal Maternal Stress (MPS) -- Epigenetics -- Childhood Exposures and Features of Asthma -- Childhood Asthma Studies and Lung Function Projections -- Allergen Exposures During Childhood -- Environmental Tobacco Smoke Around Children -- Outdoor Air Pollution and Children -- Antibiotics, the Microbiome, and Asthma in Children
Exposure to Endotoxin -- Obesity and Asthma in Children -- Gender, Puberty, and Asthma -- "It Starts Early": Effect of Female Fetus on Maternal Asthma -- Asthma Perception -- Medication Adherence Differences -- Hormonal Differences in Asthma -- Asthma of Mothers During Pregnancy -- Asthma and Menopause -- Asthma in Transgender Individuals (Role of Hormonal Switch) -- Asthma in Elders -- Back to the Paradigm of Asthma -- How Do We Engage with Our Patients Through the Lifespan of Asthma? -- Conclusion -- References -- Asthma as a Systemic Disease: Cardiovascular Effects Associated with Asthma
Background, Epidemiology of Asthma, and Cardiovascular Disease (CVD) -- Asthma, Cardiovascular Disease, and Systemic Inflammation -- Early Atherosclerotic Process: Definitions of Arterial Injury in Asthma -- Asthma and Endothelial Dysfunction in Adult Asthma Populations -- Asthma and Carotid IMT in Adult Asthma Populations -- Asthma and Arterial Stiffness in Adult Asthma Populations -- Asthma and Carotid Plaque in Adult Asthma Populations -- Asthma and Arterial Injury in Pediatric Populations -- Studies of Asthma and Atherosclerotic Cardiovascular Disease (ASCVD) Events
Summary Asthma has been challenging to treat due to its heterogeneous onset, environmental triggers, severity, and treatment response. To embrace the rapid advances in this field, Precision Approaches to Heterogeneity in Asthma follows its highly successful predecessor, Heterogeneity in Asthma. In this new volume, noted authorities Allan Brasier and Nizar Jarjour and a cadre of leaders in the field incorporate new work advancing our understanding of phenotypes (endotypes) of disease, regional variations in ventilation, systems approach to analyzing the findings from studies of inducible phenotypes, and emerging results of biomarker-informed clinical trials. This work will facilitate our current understanding of the spectrum of disease etiology, prognosis, and the likelihood of responding to the range of available therapeutic interventions.
Notes Asthma and Atherosclerotic Cardiovascular Disease: Mechanisms
Includes index
Description based on online resource; title from digital title page (viewed on October 06, 2023)
Subject Asthma.
Asthma -- Genetic aspects
Asthma -- Etiology
Asthma
Asthma
Asthma -- Etiology
Form Electronic book
Author Brasier, Allan R., editor.
Jarjour, Nizar N., editor
ISBN 9783031322594
3031322592