| Description |
1 online resource (373 pages) : illustrations (black and white, and color) |
| Contents |
Chapter 1: Introduction to Hansens disease -- Chapter 2: The journey to a scientific understanding of leprosy: a brief outline -- Chapter 3: The origin, evolution and history of leprosy through a paleopathological lens -- Chapter 4: Hansens disease and Human Rights -- Chapter 5: Leprosy agents and principal methods of detection, identification and characterization of the leprosy agents -- Chapter 6: Epidemiology of Hansens Disease -- Chapter 7: Hansens Disease and One Health -- Chapter 8: Metabolic, genetic and immunological mechanisms in susceptibility to leprosy -- Chapter 9: Clinical aspects and classification of Hansens disease -- Chapter 10: Reaction in Hansens disease -- Chapter 11: Hansens disease in children -- Chapter 12: Neuropathophysiology in Hansens disease: mechanisms of nerve injury -- Chapter 13: Neurological manifestations -- Chapter 14: Evaluation, monitoring, and prevention of disabilities in Hansens disease -- Chapter 15: Ophthalmological alterations in Hansens disease -- Chapter 16: Ear, nose, throat and mouth alterations in Hansens disease -- Chapter 17: Osteoarticular alterations in Hansens disease -- Chapter 18: Diagnostic Imaging in Hansens Disease: Conventional Radiography, Computed Tomography, Magnetic Resonance Imaging, and Dual-energy X-ray Absorptiometry -- Chapter 19: Coinfection and immunosuppression in Hansens disease -- Chapter 20: Differential diagnosis of cutaneous lesions of Hansens disease -- Chapter 21: Differential diagnoses of the neurological manifestations of Hansens disease -- Chapter 22: Immune and Chemoprophylaxis in Hansens disease -- Chapter 23: Psychosocial aspects of Hansens diseases -- Chapter 24: Peripheral Nerve by Ultrasound in Hansens Disease -- Chapter 25: Electroneuromyography in Hansens Disease -- Chapter 26: Treatment of Hansens disease |
| Summary |
Hansens disease (leprosy) is endemic in more than 100 countries worldwide, with over 200,000 new diagnoses each year and more than 4 million people living with some form of HD-related impairment. The World Health Organizations Global Leprosy Strategy timeline for Hansens disease elimination indicates that it will be encountered in clinical practice in endemic countries for at least another decade. Increasing north-to-south migration, global travel and overseas medical work mean that physicians in non-endemic countries will also encounter patients with Hansens disease, which can affect people for many years before diagnosis and after treatment. For busy clinicians, it represents a challenge, in terms of disease learning and updating knowledge and skills. This book provides a concise, up-to-date, and comprehensive source of information on Hansens disease clinical practice. It covers essential topics on all clinical aspects, complemented by history, epidemiology, paleopathology, and the social impact of the disease. Edited and written by contributors with decades of experience, its divided into twenty-six chapters clarifying the genetics and neurological manifestations, physical disabilities and its prevention; oral, ophthalmological, and bone changes, among others. For the primary audience of practicing physicians, it is an affordable point of reference, whilst also being suitable for student and trainee doctors. Its also accessible to general practitioners and specialists in dermatology, neurology, pediatrics, infectious disease, family and community medicine, and orthopedics, as well as to non-specialists and other healthcare professionals |
| Bibliography |
References -- Hansen's Disease and One Health -- 1 Animal Hosts and Zoonotic Transmission -- 2 Environmental Reservoirs and Insect Vectors -- 3 Implications for Policy and Practice -- References -- Metabolic, Genetic and Immunological Mechanisms in Susceptibility to Leprosy -- 1 Immune Activation in Disease Progression -- 2 Control of Metabolic and Immune Regulation Towards Susceptibility to Infection -- 2.1 Activation of Autophagy in Resistance and Susceptibility -- 3 Subversion Mechanisms -- 3.1 Type I IFN Pathway -- 3.2 Nutritional Immunity, Tryptophan Metabolism, IDO, and Kynurenines |
| Notes |
Description based on online resource; title from digital title page (viewed on October 12, 2023) |
| Subject |
Leprosy.
|
|
Leprosy
|
|
Leprosy.
|
| Form |
Electronic book
|
| Author |
Deps, Patrícia, editor.
|
| ISBN |
303130893X |
|
9783031308932 |
|
