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Title
Biomarkers in cancer detection and monitoring of therapeutics. Volume 2, Diagnostic and therapeutic applications / edited by Ranbir Chander Sobti, Masatoshi Watanabe, Aastha Sobti
Published
London : Academic Press, [2024]
Click on the following:
ScienceDirect eBooks
Copies
Description
1 online resource
Contents
Intro
-
- Biomarkers in Cancer Detection and Monitoring of Therapeutics: Volume 2: Diagnostic and Therapeutic Applications
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- Copyright
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- Contents
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- Contributors
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- Preface
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- Chapter One: Oral squamous cell carcinoma
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- 1. Oral cancer
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- 2. Oral squamous cell carcinoma
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- 3. Epidemiology
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- 4. Etiology
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- Impact of tobacco products
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- Patterns and trends in tobacco use
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- Use of smokeless tobacco products
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- 5. Precursor lesions
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- 5.1. Genetically acquired potentially malignant
disorders
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- 5.2. Tobacco-induced potentially malignant
disorders
5.3. Immune-mediated potentially malignant
disorders
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- 5.4. Genetically inherited potentially malignant
disorders
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- 6. Oral epithelial dysplasia
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- 7. Pathogenesis
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- 7.1. Autophagy
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- 8. Cancer stem cells
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- 9. Tumor microenvironment
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- 10. Epithelial-mesenchymal transition
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- 11. Metastasis
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- 12. Oral bacteria in oral carcinogenesis
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- 13. Clinical features
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- Salient features specific to subsite
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- 14. Diagnosis
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- 14.1. Adjunctive aids for early detection
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- Nano-diagnostics
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- Lab-on-chip/microfluidics
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- Liquid biopsy
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- Microarray technology
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- Next generation sequencing
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- Omics
Genomics
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- Transcriptomics
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- Proteomics
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- Metabolomics
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- Staging of oral squamous cell carcinoma
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- 15. Histopathological features
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- 16. Treatment
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- 16.1. Surgical resection
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- Management of primary lesion
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- Management of neck nodes
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- 16.2. Chemotherapy
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- Adjuvant chemotherapy
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- Adjuvant chemoradiotherapy
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- Primary chemoradiation
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- Induction chemotherapy
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- In the management of metastatic disease
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- 16.3. Nanotechnology in carcinoma therapy
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- Chemoprevention using nanoparticles
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- 16.4. Radiotherapy
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- 16.5. Immunotherapy
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- Cytokines
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- Toll-like receptors
Immune checkpoint inhibitors
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- Immune checkpoint activators
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- 16.6. Therapeutic markers
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- 17. Prognosis
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- 17.1. Clinical factors
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- 17.2. Histopathological factors
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- 17.3. Metastasis
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- References
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- Chapter Two:
Genetic
predisposition and pathophysiology of oral squamous cell carcinoma
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- 1. Introduction
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- 1.1. Microbial flora
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- 1.2. Oral microbial flora
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- 1.3. Oral microbial flora and cancer
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- 1.4. Squamous cell carcinoma of the head and neck
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- 2. Oral squamous cell carcinoma and glucose transporters
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- 2.1. Human glucose transporters
2.2. Glucose transporters (GLUT 1) and its expression
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- 3. Oral squamous cell carcinoma and methylated genes
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- 3.1. Variation of methylated genes in cancer conditions
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- 3.2. DNA methylation modifications and its implications
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- References
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- Chapter Three: Molecular biomarkers in gastric cancer
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- 1. Introduction
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- 2. RNF43
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- 3. APC
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- 4. ARID1A
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- 5. ARID2
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- 6. MSI
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- 7. MALTA1-GLT1 fusion
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- 8. TP53
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- 9. RB1
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- 10. ERBB2
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- 11. C-MET
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- 12. EGFR
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- 13. PD-L1
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- 14. Epstein-Barr virus
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- 15. VEGF-A
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- 16. CD44
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- 17. E-cadherin
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- 18. Matrix metalloproteinases (MMPs)
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- 19. Conclusions
Notes
Print version record
Subject
Tumor markers
-
- Diagnostic use.
Tumor markers
-
- Therapeutic use
Tumor markers
-
- Diagnostic use
Form
Electronic book
Author
Sobti, Ranbir Chander
Watanabe, Masatoshi
Sobti, Aastha
ISBN
9780323951159
0323951155
Other Titles
Diagnostic and therapeutic applications
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