| Description |
1 online resource (476 p.) |
| Contents |
Color Atlas of Genetics -- At a Glance -- Dedication -- Title Page -- Copyright -- Preface -- Acknowledgments -- About the Author -- Table of Contents -- Introduction -- Chronology -- Important Advances that Contributed to the Development of Genetics -- Fundamentals -- Prologue -- Phylogenetic Tree of Living Organisms -- Origins of Humans -- Out of Africa: Toward Modern Humans -- The Cell and Its Components -- Genetic Background of Aging Processes -- Molecular Basis of Genetics -- Carbohydrates -- Lipids (Fatty Acids) -- Amino Acids -- Nucleotides and Nucleic Acids -- DNA and Its Components |
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DNA as a Carrier of Genetic Information -- DNA Structure -- DNA Replication -- The Flow of Genetic Information: Transcription and Translation -- Genetic Code -- Eukaryotic Gene Structure -- Analysis of DNA -- Restriction Enzymes -- DNA Amplification (PCR) -- DNA Sequencing -- Parallel DNA Sequencing (Next-Generation Sequencing) -- DNA Cloning -- DNA Libraries -- Southern Blot Hybridization -- Variability of DNA -- DNA Variants -- Genes and Mutation -- Mutations Due to Base Modifications -- Mutations Due to Errors in Replication -- Processing of DNA -- DNA Repair Systems -- Transposition |
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Trinucleotide Repeat Expansion -- Eukaryotic Cells -- Cell Communication -- Haploid and Diploid Yeast Cells -- Cell Cycle Control -- Cell Division: Mitosis -- Meiosis in Germ Cells -- Meiosis Prophase I -- Formation of Gametes -- Programmed Cell Death -- Cultured Cells -- Formal Genetics -- The Mendelian Traits -- Transmission to the Next Generation -- Independent Distribution -- Phenotype and Genotype: Application in Genetic Counseling -- Segregation of Parental Genotypes -- Monogenic Inheritance -- Genetic Linkage and Recombination -- Genetic Linkage and Association Analysis |
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Quantitative Differences in Genetic Traits -- Distribution of Alleles in a Population -- Hardy-Weinberg Equilibrium Principle -- Geographical Differences in Allelic Distribution -- Inbreeding -- Twins and Twinning -- Chromosomes -- Chromosomes and Genes -- Chromosome Organization -- Functional Elements of Chromosomes -- Nucleosomes -- Packing DNA in Chromosomes -- The Telomere -- Chromosomes in Metaphase -- The Banding Patterns of Human Chromosomes -- Karyotype of Man and Mouse -- Preparation of Metaphase Chromosomes for Analysis -- Fluorescence in Situ Hybridization |
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Multicolor Fluorescence In Situ Hybridization (FISH) Identification of Chromosomes -- Aneuploidy -- Chromosome Translocation -- Structural Chromosomal Aberrations -- Regulation of Gene Function -- Ribosomal RNA and Protein Assembly -- Stages of Transcription -- Basic Principles of Gene Control -- Regulation of Gene Expression in Eukaryotes -- DNA-Protein Interactions -- Other Forms of Transcription Control -- Noncoding RNAs -- Targeted Gene Disruption -- Epigenetic Modifications -- DNA Methylation -- Reversible Changes in Chromatin Structure -- Genomic Imprinting |
| Summary |
Ever since the International Human Genome Project achieved its extraordinary goal of sequencing and mapping the entire human genome, represented by approximately 3 billion base pairs, with its far-reaching implications for understanding the causes of human genetic disorders and their diagnosis, progress in the field has not slowed down. In the fifth edition of the bestselling Color Atlas of Genetics, readers will be rewarded with a complete and current overview of the field, with an emphasis on the interface between fundamental principles and practical applications in medicine and the role of |
| Notes |
Description based upon print version of record |
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Mammalian X Chromosome Inactivation |
| Subject |
Medical genetics.
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Genetics, Medical
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Medical genetics.
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| Form |
Electronic book
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| ISBN |
9783132414419 |
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3132414417 |
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