| Description |
1 online resource (xviii, 349 pages) : colour illustrations |
| Contents |
Why Context Matters: Understanding Social and Behavioural Aspects of Antimicrobial Use and Resistance in Africa -- Antimicrobial Stewardship in Africa -- Etiology of Early-Onset Bacterial Sepsis and Antibiotic Resistance in Neonates: A Case Study in an Algerian Neonatal Intensive Care Unit -- Genetics of Viral Resistance: Clinical Relevance and Role in Viral Disease Outbreak -- Distribution and Prevalence of Antimicrobial Resistance of NTS Salmonella Isolated from Farm Animals and Animal Food Products in Africa -- The Current Status of Antibiotic-Resistant Bacteria and Resistance Genes in African Aquaculture -- Occurrence and Health Risks of Antibiotic Resistance in African Aquatic Systems -- The Current State of Antimicrobial Use in Bovine Mastitis in Various African Countries -- Microbiological Safety and Antimicrobial Resistance in Fresh Produce Production in Africa -- Biosecurity and Disinfectant Resistance in a Post-antibiotic Era -- The Linkage Between Antibiotic and Disinfectant Resistance -- The Use of Nanomaterials for the Elimination of Antibiotic-Resistant Bacteria from Water and Wastewater: An African Overview -- Biocidal Activity of Plant Extracts: The Case of Algeria -- The Combined Use of African Natural Products and Conventional Antimicrobials: An Alternative Tool Against Antimicrobial Resistance |
| Summary |
Antimicrobial resistance is recognised among the worlds most challenging problems. Despite its global spread, Africa, specifically sub-Saharan Africa, is the most affected by this malaise. Poor living conditions and inadequate access to sanitation and potable water supplies are among contributing factors that have influenced a high disease burden on the continent, requiring extensive antimicrobials. Weak health systems and the absence of firm policies further aggravate the problem, as the use of antimicrobials is mostly unregulated. The increasing demand for animal protein to meet the starving populations demands has also influenced the use of these antimicrobials, including those banned on other continents, for food animal production. The ripple effect of indiscriminate use in humans and animals is the massive discharge of antimicrobials, their residues, antimicrobial-resistant microorganisms and their associated genes into the environment. This 14-chapter text presents the AMR problem in African, addressing the various compartments of One Health humans, animals, and the environment, to illustrate the need for concerted efforts in the fight against AMR. Authors from the four cardinal points present diverse aspects of AMR in Africa, starting with behavioural and social drivers of AMR in Africa. Antimicrobial stewardship in an African context is also discussed. AMR in humans is presented through studies on antibiotic-resistant neonates and nontyphoidal Salmonella infections and the clinical relevance of the genetics of viral resistance. Topics on AMR in mastitis, biosecurity in animal farming and the linkage between disinfectants and AMR are discussed. The environmental dimension of AMR is discussed, notably in the aquatic environment, and its implication for aquaculture and irrigation and using nanomaterials to treat polluted waters from such environments are highlighted. Finally, Africas rich floral diversity is portrayed as an eco-friendly and cost-effective approach to combat AMR. Hopefully, the work presented will spur greater collaboration between scientists, environmental, animal and human health practitioners, the general population, and policymakers to assimilate and implement the One Health approach to combating AMR, rather than working in silos in their various sectors |
| Bibliography |
Includes bibliographical references and index |
| Notes |
Description based on online resource; title from digital title page (viewed on March 20, 2023) |
| Subject |
One Health (Initiative)
|
| SUBJECT |
One Health (Initiative) fast |
| Subject |
Anti-infective agents -- Africa
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Drug resistance.
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Public health -- Africa
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Drug Resistance
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Anti-infective agents
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Drug resistance
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Public health
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Africa
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| Form |
Electronic book
|
| Author |
Abia, Akebe Luther King, editor.
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Essack, Sabiha Yusuf, editor
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| ISBN |
303123796X |
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9783031237966 |
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