Description |
1 online resource (xv, 412 pages) : illustrations |
Series |
Contemporary clinical neuroscience |
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Contemporary clinical neuroscience.
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Contents |
GPCRs: Structure and Function -- Structure--Function Relationships in G Protein-Coupled Receptors -- Molecular Mechanisms Involved in the Activation of Rhodopsin-Like Seven-Transmembrane Receptors -- GPCR Folding and Maturation -- Regulated Membrane Trafficking and Proteolysis of GPCRs -- GPCR Activity and Its Regulators -- Heterotrimeric G Proteins and Their Effector Pathways -- RGS Proteins -- G Protein-Coupled Receptor Kinases -- Regulators of GPCR Activity -- GPCR Interacting Proteins -- GPCR Dimerization/Oligomerization -- Biophysical and Biochemical Methods to Study GPCR Oligomerization -- Oligomerization Domains of G Protein-Coupled Receptors -- Functional Complementation and the Analysis of GPCR Dimerization -- The Role of Oligomerization in G Protein-Coupled Receptor Maturation -- Receptor Oligomerization and Trafficking -- Modulation of Receptor Pharmacology by G Protein-Coupled Receptor Dimerization -- Recent Developments in Drug Discovery -- Role of Heteromeric GPCR Interactions in Pain/Analgesia -- Conformational Plasticity of GPCR Binding Sites -- De-Orphanizing GPCRs and Drug Development |
Summary |
"The G Protein-Coupled Receptors Handbook offers pharmacologists, biochemists, and neuroscientists an exhaustive review of the progress made in understanding how GPCRs are activated and regulated, key factors in exploiting GPCRs for drug development."--Jacket |
Bibliography |
Includes bibliographical references and index |
In |
OhioLINK electronic book center |
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SpringerLink |
Subject |
G proteins -- Receptors -- Handbooks, manuals, etc
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G proteins.
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G proteins -- Receptors
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Receptors, G-Protein-Coupled
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GTP-Binding Proteins
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MEDICAL -- Histology.
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Biomédecine.
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Sciences de la vie.
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G proteins
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G proteins -- Receptors
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Genre/Form |
Electronic books
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handbooks.
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Handbooks and manuals
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Handbooks and manuals.
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Guides et manuels.
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Form |
Electronic book
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Author |
Devi, Lakshmi A.
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LC no. |
2004024043 |
ISBN |
1588293653 |
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9781588293657 |
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9781592599196 |
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1592599192 |
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