| Description |
1 online resource (747 p.) |
| Contents |
Cover -- Half Title -- Title Page -- Copyright Page -- Dedications -- Contents -- Preface -- Acknowledgments -- Editors -- Contributors -- 1. Journey from Macromolecular Pathology to Molecular Therapies -- 2. Global Epidemiology of CF: High-Income and Low-/Middle-Income Countries (Global Harmonization Registry Countries) -- 3. Voices of Patients and Families -- 4. Patient Organisations -- 5. Molecular Biology of CFTR: From the Gene to the Protein -- 6. Biology of the CF Airway Epithelium -- 7. The Physiology of Epithelial Ion and Fluid Transport: Beyond CFTR Modulators |
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8. Inflammation in Cystic Fibrosis -- 9. Model Organisms of Cystic Fibrosis -- 10. Systems Biology and the New Omics -- 11. Genotype: Phenotype Correlations -- 12. Gene Environment Interactions -- 13. Demographic, Socioeconomic, and Environmental Contributions to Health in Cystic Fibrosis -- 14. Drug Discovery Platforms for CFTR Modulators -- 15. CFTR Modulator Drug Discovery and Translation into the Clinic -- 16. Newborn and Carrier Screening for CF -- 17. Diagnostic Tests: Sweat Testing, Epithelial Potential Differences and Genetic Testing |
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18. Immediate Management of the Newly Screened Positive Baby -- 19. Diagnosis of the Symptomatic Patient -- 20. Blurred Boundaries: CRMS/CFSPID and CFTR-Related Disorders -- 21. Respiratory Disease across the Lifecourse -- 22. Respiratory Effects of the New CFTR Modulators -- 23. Epidemiology and Microbiology of Cystic Fibrosis Pulmonary Infections -- 24. New Methods for Detecting and Identifying Bacteria -- 25. Non-Tuberculous Mycobacterial Infections in Cystic Fibrosis -- 26. Fungal Diseases in CF -- 27. Molecular Microbiology of the CF Gut and Lung |
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28. Pulmonary Exacerbations in Cystic Fibrosis: Epidemiology, Treatment, Outcomes, and Future Research -- 29. Infection Prevention and Control in Cystic Fibrosis -- 30. Technology in Cystic Fibrosis Therapies -- 31. Upper Airway Disease in Cystic Fibrosis -- 32. Gastrointestinal Disease in CF -- 33. Cystic Fibrosis Liver Disease -- 34. Cystic Fibrosis-Related Diabetes -- 35. Growth in Cystic Fibrosis: Is Chloride Transport the Key? -- 36. Bone Disease in Cystic Fibrosis -- 37. Cancer and Cystic Fibrosis -- 38. Other Cystic Fibrosis-Related Diseases and Complications |
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39. Extrapulmonary Benefits of the New CFTR Modulator Drugs -- 40. Sexual Health, Fertility, and Pregnancy in People with Cystic Fibrosis -- 41. Mental Health Issues in Cystic Fibrosis -- 42. Adherence and Self-Management in Cystic Fibrosis Care -- 43. Transplantation -- 44. Working with Cystic Fibrosis -- 45. Growing Old with Cystic Fibrosis -- 46. Imaging of Cystic Fibrosis Lung Disease -- 47. Lung Function Testing Including Multiple Breath Washout -- 48. Infant Pulmonary Function Tests -- 49. Exercise Testing in Cystic Fibrosis -- 50. Bronchoscopy and Bronchoalveolar Lavage in Cystic Fibrosis |
| Notes |
Description based upon print version of record |
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51. Patient-Derived Cell-Based Models for Theratyping and Individual CFTR Modulator Assessment |
| Form |
Electronic book
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| Author |
Amaral, Margarida D
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Davies, Jane C
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Simmonds, Nicholas J
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Taylor-Cousar, Jennifer L
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Ranganathan, Sarath C
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| ISBN |
9781000988536 |
|
1000988538 |
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