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Book Cover
E-book
Author Choi, Andy H

Title Calcium phosphate nanocoatings for bone regeneration / Andy H. Choi, Besim Ben-Nissan
Published Singapore : Springer, 2023

Copies

Description 1 online resource (89 p.)
Series Tissue repair and reconstruction
Tissue repair and reconstruction
Contents Intro -- Preface -- Contents -- 1 Introduction -- References -- 2 Why Surface Modification -- References -- 3 Calcium Phosphate -- References -- 4 Mechanical Integrity of Thin Films and Coatings and Their Clinical Significance -- 4.1 Determining Stresses in Thin Films and Coatings -- 4.2 Interfacial Adhesion Between a Coating and a Substrate -- 4.3 Coating Adhesion and Mechanical Interlocking -- 4.4 Enhancing the Adhesion of Nanocoatings to Titanium via Anodization Process -- 4.5 Adhesion Theories Based on Chemical Bond, Electrostatic, and Diffusion
4.6 Characterizing Coatings and Nanocoatings Mechanically Prior to Implantation -- 4.6.1 In Situ Microtensile Test -- 4.6.2 Shear and Tensile Pull-Off Testing -- 4.6.3 Nanoindentation Testing -- 4.6.4 Bend Delamination Test -- 4.6.5 Bulge and Blister Testing -- 4.6.6 Scratch Testing -- 4.6.7 Pin-on-Disk -- References -- 5 Coating Deposition Techniques -- 5.1 Coatings Produced by Plasma Spraying -- 5.2 Comparison Between Coatings Produced by Plasma Spraying and Sol-Gel Technique -- 5.3 The Sol-Gel Deposition Approach -- 5.3.1 The Alkoxide Route -- 5.4 Other Coating Deposition Techniques
5.4.1 Pulsed Laser Deposition -- 5.4.2 Physical and Chemical Vapor Depositions -- 5.4.3 Electrodeposition -- References -- 6 Cellular Responses -- References -- 7 Enhancing Implant Osseointegration Through Nanocomposite Coatings -- 7.1 Collagen -- 7.2 Chitosan -- 7.3 Bone Morphogenetic Proteins (BMPs) -- 7.4 Peptides -- 7.5 Stem Cells -- 7.6 Functionalization Using Osteopontin -- 7.7 Simvastatin -- References -- 8 Calcium Phosphate Nanocoated Coralline Apatite -- References
Summary This book provides in-depth assessment on the latest clinical advances in multifunctional calcium phosphate nanocoatings and its influence on bone regeneration and early healing following implantation. A greater emphasis will be placed on the use of nanocomposite coatings to deliver biological materials such as mesenchymal stem cells, growth factors, bone morphogenetic and extracellular matrix proteins, and pharmaceutics such as simvastatin to improve and promote bone growth as well as reducing the timeframe needed for implant integration in both healthy and osteoporotic patients. The content of the book caters to clinical practitioners and researchers working in the field of biomaterials for bone regeneration
Bibliography Includes bibliographical references
Notes Online resource; title from PDF title page (SpringerLink, viewed September 27, 2023)
Subject Nanostructured materials -- Therapeutic use
Bone regeneration -- Technological innovations
Thin films.
Calcium phosphate.
Calcium Phosphates
Form Electronic book
Author Ben-Nissan, B.
ISBN 9789819955060
9819955068