Title Regional cancer therapy / edited by Peter M. Schlag, Ulrike Stein ; foreword by Alexander M.M. Eggermont

Published Totowa, N.J. : Humana Press, ©2007

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Description 1 online resource (xiv, 455 pages) : illustrations (some color) Series Cancer drug discovery and development Cancer drug discovery and development. Contents Background -- Biological Background -- Pharmacological Background -- Isolated Limb and Organ Perfusion Laboratory Models -- Techniques and Prerequisites for Regional Therapy -- Interventional Radiotherapy -- Surgical Strategies -- Regional Thermotherapy -- Radiofrequency Thermal Ablation -- Cryoablation for Primary and Secondary Liver Tumors -- A Personal History of Photodynamic Therapy -- Ultrasound-Guided Therapy -- Nanocarriers and Drug Delivery -- Local Gene Therapy for Cancer -- Indications and Results for Different Tumor Entities -- Regional Chemotherapy of Primary and Metastatic Liver Tumors -- Focal Liver Ablation Techniques in Primary and Secondary Liver Tumors -- Regional Therapy for Peritoneal Surface Malignancy -- Malignant Peritoneal Mesothelioma -- Regional Therapy of Pancreatic Cancer -- Regional Breast Cancer Treatment -- Regional Therapy in Ovarian Cancer -- Regional Therapy of Bladder Tumors -- Regional Therapy of Rectal Cancer -- Percutaneous Laser Ablation of Lung Metastases -- Regional Therapy of Brain Tumors -- Hyperthermic Intrapleural Chemotherapy in Pleural Malignancy -- Isolated Limb Perfusion in Advanced Soft Tissue Sarcomas -- Isolated Limb Perfusion for Melanoma in Transit Metastases -- Outpatient Brachytherapy with Seeds Summary This volume provides a biological and pharmacological background for regional cancer therapy, strategies and techniques for regional therapies, and specific indications and results for different tumor entities. Clinical trial concepts and detailed treatment protocols are also presented. Part I describes biological and pharmacological fundamentals for therapy and introduces laboratory models for isolated limb and organ perfusion. Topics introduced in Part II include interventional radiotherapy, surgical strategies, regional thermotherapy, radiofrequency thermal ablation, cryoablation, nanocarriers and drug delivery, and local gene therapy for cancer. Highlights of Part III include regional chemotherapy of primary and metastatic liver tumors and focal liver ablation techniques in primary and secondary liver tumors. "Regional Cancer Therapy" is essential reading for researchers and clinicians engaged in seeking advanced therapeutic options for cancer patients worldwide Analysis neoplasms radiotherapie radiotherapy chirurgie surgery biomedische wetenschappen biomedicine oncologie oncology Medicine (General) Geneeskunde (algemeen) Bibliography Includes bibliographical references and index Notes Print version record In Springer e-books Subject Cancer -- Chemotherapy. Drug targeting. Infusion therapy. Antineoplastic agents -- Administration Isolation perfusion (Physiology) Multidrug resistance. Drug resistance in cancer cells. Surgery. Neoplasms -- therapy Drug Delivery Systems Chemotherapy, Cancer, Regional Perfusion Combined Modality Therapy -- methods Drug Resistance, Multiple Drug Resistance, Neoplasm General Surgery surgery (health care function) MEDICAL -- Oncology. HEALTH & FITNESS -- Diseases -- Cancer. Drug targeting. Infusion therapy. Antineoplastic agent -- Administration. Neoplasms -- therapy. Chemotherapy, Cancer, Regional Perfusion. Combined Modality Therapy -- methods. Drug Resistance, Multiple. Drug Resistance, Neoplasm. Cancer -- Chemotherapy. Biomédecine. Sciences de la vie. Multidrug resistance Isolation perfusion (Physiology) Drug resistance in cancer cells Antineoplastic agents -- Administration Cancer -- Chemotherapy Drug targeting Infusion therapy Form Electronic book Author Schlag, P. (Peter), 1948- Stein, Ulrike LC no. 2006015503 ISBN 9781597452250 1597452254 1588296725 9781588296726 1280971541 9781280971549

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