| Description |
1 online resource |
| Contents |
Intro -- Preface to First Edition -- Acknowledgment -- Contents -- 1: Pathophysiology: General Principles -- 1.1 Introduction -- 1.2 Pathology -- 1.3 Definition of Disease -- 1.3.1 Homeostasis -- 1.3.2 The Genome -- 1.4 Physiology -- 1.5 Pathophysiology -- 1.6 Basic Major Principles of Pathophysiology -- 1.6.1 Cell Injury -- 1.6.1.1 Biochemical Cell Injury Mechanisms -- 1.6.1.2 Intracellular Accumulations -- 1.6.2 Cell and Tissue Response to Injury -- 1.6.2.1 Cell Adaptation -- 1.6.2.1.1 Atrophy -- 1.6.2.1.2 Hypertrophy -- 1.6.2.1.3 Hyperplasia -- 1.6.2.1.4 Metaplasia |
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1.6.2.1.5 Dysplasia -- 1.6.2.2 Cell Death -- 1.6.2.2.1 Necrosis (Nonregulated, Inflammatory Accidental Cell Death) -- 1.6.2.2.2 Apoptosis (Regulated, Noninflammatory Cell Death) -- References -- 2: Ionizing Radiation: Biologic Effects and Essential Cell and Tissue Biology -- 2.1 Essential Cell and Tissue Biology -- 2.1.1 Cell Structure and Function -- 2.1.1.1 Plasma Membrane -- 2.1.1.2 Cytoplasm and its Organelles -- 2.1.1.2.1 The Endoplasmic Reticulum -- 2.1.1.2.2 The Golgi Complex -- 2.1.1.2.3 Lysosomes -- 2.1.1.2.4 Peroxisomes -- 2.1.1.3 Mitochondria -- 2.1.1.4 Ribosomes |
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2.1.1.5 Cytoskeleton -- 2.1.1.6 Nucleus -- 2.1.2 The Genetic Material and Gene Expression -- 2.1.2.1 The Genetic Material: DNA -- 2.1.2.1.1 DNA Structure -- 2.1.2.1.2 DNA Replication -- 2.1.2.1.3 DNA Mutation -- 2.1.2.1.4 DNA Recombination -- 2.1.2.2 Gene Expression and Protein Synthesis -- 2.1.2.3 Genetic Code -- 2.1.2.4 DNA Translation: Protein Synthesis -- 2.1.3 Cell Reproduction -- 2.1.3.1 The Cell Cycle -- 2.1.3.2 Mitosis and Cytokinesis -- 2.1.3.3 Rates of Cell Division -- 2.1.3.4 Chromosomes and Diseases -- 2.1.4 Cell Transformation and Differentiation |
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2.1.5 Normal and Malignant Growth -- 2.1.5.1 Normal Growth -- 2.1.5.1.1 Types of Cells and Tissue -- 2.1.5.1.2 MuscleTissue -- Skeletal Muscle -- Cardiac Muscle -- Smooth Muscle -- 2.1.5.1.3 Nerve Tissue -- 2.1.5.1.4 Epithelial Tissue -- 2.1.5.1.5 Matrix -- 2.1.5.2 Indigenous Connective Tissue -- 2.1.5.2.1 Fibroblasts -- 2.1.5.2.2 Mast Cells -- 2.1.5.2.3 Fat Cells -- 2.1.5.2.4 Bone Cells -- 2.1.5.2.5 Cartilage Cells -- 2.1.5.2.6 Immigrant Cells -- 2.1.5.3 Neoplastic Growth -- 2.1.6 Cellular Metabolism -- 2.1.6.1 Role of ATP -- 2.1.6.2 Production of ATP -- 2.1.6.2.1 Glycolysis |
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2.1.6.2.2 Oxidative Phosphorylation -- 2.1.7 Transport through the Cell Membrane -- 2.1.7.1 Transport of Water and Solutes -- 2.1.7.1.1 Diffusion -- 2.1.7.1.2 Active-Mediated Transport -- 2.1.7.1.3 Transport by Vesicle Formation -- 2.1.7.1.4 Transport by Transmission of Electrical Impulses -- 2.1.8 Cell Death (See also Chaps. 1 and 12) -- 2.1.8.1 Imaging Cell Death -- 2.2 Biologic Effects of Ionizing Radiation -- 2.2.1 Ionizing Radiation -- 2.2.2 Mechanisms of Radiation Effects -- 2.2.2.1 Direct Effect -- 2.2.2.2 Indirect Effect -- 2.2.2.2.1 Bystander Effect |
| Summary |
This book, now in its second edition, will serve as a quick reference that will help the reader to understand different diagnostic scintigraphic patterns and to select appropriate treatment modalities based on functional imaging. The book concisely describes relevant anatomic and physiologic considerations for each organ system and the pathophysiologic features of different relevant diseases and relates them to the scintigraphy of each system. It thereby provides an informative synopsis of the pathophysiologic basis of nuclear medicine and molecular imaging. The volume is divided into 13 chapters that feature basic pathophysiology, cell biology and biologic effects of ionizing radiation, radiopharmaceutical uptake and relevant anatomic and physiologic considerations for each organ system and the pathophysiologic features of different relevant diseases. The objective of this volume is to provide a brief, easy to-use but nonetheless comprehensive companion guide to The Pathophysiology Basis of Nuclear Medicine that will prove useful to undergraduates and postgraduates as well as to practitioners in clinical and research fields |
| Bibliography |
Includes bibliographical references |
| Notes |
Online resource; title from PDF title page (SpringerLink, viewed July 12, 2023) |
| Subject |
Nuclear medicine.
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Physiology, Pathological.
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Nuclear Medicine
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Nuclear medicine
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Physiology, Pathological
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| Form |
Electronic book
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| ISBN |
9783031206467 |
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3031206460 |
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