| Description |
pages ; cm |
| Contents |
Inflammatory mechanisms in Alzheimer's disease and other neurodegenerative disorders / J. Rogers ... [et al.] -- Treatment development strategies for Alzheimer's disease / E. Wülfert -- Lipoprotein-associated phospholipase A2 as a new prognostic factor for coronary artery disease / A. Tselepis -- Protein modifications by nitric oxide and reactive nitrogen species / H. Ischiropoulos -- Design, synthesis, and pharmacological evaluation of high affinity and selectivity sigma-1 and sigma-2 receptor ligands / J.H. Poupaert -- Synthesis of biologically active taxoids / K.C. Nicolaou and R.K. Guy -- From the molecular pharmacology to the medicinal chemistry of cannabinoids / D.M. Lambert -- New inhibitors of DNA topoisomerase in the treatment of experimental malignancies / C. Atassi -- Treatment of psoriasis with anthrones-biochemical aspects / W. Wiegrebe and K. Müller -- An appraisal of fomocaines, current situation, and outlook / H. Oelschläger and A. Seeling -- Ligands for the GABA recognition site at the GABAA receptor: structure-activity studies / B. Frølund ... [et al.] -- Discovery of potent and selective inhibitors of human aldosterone synthase (CYP11B2): a new target for the treatment of congestive heart failure and myocardial fibrosis: a review / R.W. Hartmann ... [et al.] -- |
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Thiocarboxanilides: a new class of non-nucleoside reverse transcriptase inhibitors (NNRTIS) with great potential for the treatment of human immunodeficiency virus type 1 (HIV-1) infections / E. De Clercq, A. Karlsson, and J. Balzarini -- Histamine H3-receptor agonists and antagonists: chemical, pharmacological, and clinical aspects / H. Stark and W. Schunack -- Anti-inflammatory actions of flavonoids and structural requirements / T. Theoharides -- Molecular mechanisms of H2O2-induced DNA damage: the action of desferrioxamine / M. Tenopoulou, P.-T Doulias, and D. Galaris -- LNA (locked nucleic acid) and functionalized LNA: towards efficient gene targeting / J. Wengel -- The effect of diet on drug metabolism / K.J. Netter -- Cytochromes P450 in the metabolism and bioactivation of chemicals / C. Ioannides -- In vitro methods to measure drug metabolism and metabolic interactions in drug discovery and development / O. Pelkonen ... [et al.] -- How to probe the sites of action of drug molecules / A. Makriyannis and F. Bitter -- Lipophilicity as a descriptor of molecular properties in drug design / B. Testa ... [et al.] -- Drug membrane interaction and the importance for drug transport, distribution, accumulation, efficacy, and resistance / J.K. Seydel ... [et al.] -- Structure-based and computer-aided drug design / H. Kubinyi -- Physicochemical profiling in early drug discovery: new challenges at the age of high-throughput screen and combinatorial chemistry / B. Faller |
| Notes |
"A CRC title." |
| Bibliography |
Includes bibliographical references and index |
| Subject |
Pharmaceutical chemistry.
|
|
Drugs -- Design.
|
|
Chemistry, Pharmaceutical.
|
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Drug Design.
|
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Pharmacologic Actions.
|
| Author |
Kourounakis, P. N.
|
|
Rekka, E. A.
|
| LC no. |
2007010012 |
| ISBN |
9780849390067 hardcover alkaline paper |
|
0849390060 hardcover alkaline paper |
|
