| Description |
1 online resource (xiv, 294 pages) : illustrations |
| Contents |
Cover13; -- Contents -- Preface -- Acknowledgments -- About the Editors -- Contributors -- Section I: Folding and Stability of Metalloproteins -- Chapter 1: Metal Ions, Protein Folding, and Conformational States -- Chapter 2: The Folding Mechanism of c-Type Cytochromes -- Chapter 3: The Mechanism of Cytochrome c Folding -- Chapter 4: Stability and Folding of Copper-Binding Proteins -- Chapter 5: Iron-Sulfur Clusters, Protein Folds, and Ferredoxin Stability -- Chapter 6: Folding and Stability of Myoglobins and Hemoglobins -- Section II: Mechanisms of Metal Transporters and Assembly -- Chapter 7: Frataxin -- Chapter 8: Mechanism of Human Copper Transporter Wilsons Disease Protein -- Section III: Metal Ions, Protein Conformation, and Disease -- Chapter 9: 945;-Synuclein and Metals -- Chapter 10: Zinc and p53 Misfolding -- Chapter 11: The Octarepeat Domainof the Prion Protein and Its Role in Metal Ion Coordination and Disease -- Section IV: Metalloprotein Design, Simulation, and Models -- Chapter 12: Metallopeptides asTools to UnderstandMetalloprotein Folding and Stability -- Chapter 13: The Folding Landscapes of Metalloproteins -- Appendix -- Back cover |
| Summary |
"Interest in the uses and applications of metallo-chemistry in the life sciences continues to expand. This book provides a broad overview of metals and protein folding. It addresses fundamental aspects of the folding, stability, and design of metal binding proteins and peptides along with biological aspects related to the action of metallochaperones. The text features practical information related to methodologies, particular techniques, and bibliographic references. Readers will gain the molecular basis for protein-metal interactions and a good perspective on the applications of protein coordination chemistry in life sciences and biotechnology"--Provided by publisher |
| Bibliography |
Includes bibliographical references and index |
| Notes |
Print version record |
| Subject |
Metalloproteins.
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Protein folding.
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Proteins -- Conformation.
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Metalloproteins
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Metallochaperones
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Protein Conformation
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Protein Folding
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Protein Stability
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SCIENCE -- Life Sciences -- Biochemistry.
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Proteins -- Conformation
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Metalloproteins
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Protein folding
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| Form |
Electronic book
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| Author |
Gomes, Cláudio M., 1970- editor.
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Wittung-Stafshede, Pernilla, 1968- editor.
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| ISBN |
9781439809655 |
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1439809658 |
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