| Description |
1 online resource (XX, 414 pages 184 illustrations, 156 illustrations in color.) : online resource |
| Contents |
Intro; Preface; Acknowledgments; Contents; List of Editors and Associate Editors; Part I: Essential Basic Considerations in Colorectal Cancer; 1: Epidemiology of Colorectal Cancer in Asia-Pacific Region; 1.1 Trends of Colorectal Cancer Incidence and Mortality; 1.1.1 Temporal Trends; 1.1.2 Geographic Variations; 1.1.3 Survival of Colorectal Cancer Patients; 1.2 Risk Factors; 1.2.1 Smoking; 1.2.2 Alcohol Drinking; 1.2.3 Meat Consumption; 1.2.4 Obesity and Physical Inactivity; 1.2.5 Fruits and Vegetables; 1.2.6 Soy Product and Green Tea Consumption |
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1.2.7 Dairy Product and Whole Grains1.2.8 Migrant Studies; References; 2: A Multidisciplinary Approach for Advanced Colorectal Cancer; 2.1 Definition and Team Composition; 2.2 Increasing Need for Clinical MDTs and a Brief Introduction to Our Experience of a MDT; 2.3 Impact of MDT; 2.3.1 Changes in Decision- Making and Subsequent Treatment Plans; 2.3.2 Increasing Adherence to Treatment Guidelines; 2.3.3 Improvement of Surgical Outcomes; 2.3.4 Impact on Patient Satisfaction and Quality of Life; 2.3.5 Impact on Survival |
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2.3.6 Impact on Research and Evidence-Making Process and Education2.4 Debate on Efficacy of MDT; 2.5 Factors Affecting the Efficacy of MDT Clinics; 2.5.1 Time Pressure and Inadequate Information; 2.5.2 Leadership and Team Culture; 2.5.3 Infrastructures and Decision Support System; 2.5.4 Feedback on MDT Performance; 2.6 Future Perspectives; References; 3: Molecular Basis of Colorectal Cancer: Tumor Biology; 3.1 Introduction; 3.2 Three Molecular Carcinogenesis Pathways and Two Morphologic Multistep Pathways; 3.3 CIN; 3.3.1 Defects in Chromosomal Segregation |
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3.3.2 Centromere Dysfunction3.3.3 Telomere Dysfunction; 3.3.4 Loss of Heterozygosity (LOH); 3.3.5 Deficiencies in DNA Damage Response; 3.3.6 Clinical Implications of CIN; 3.4 MSI; 3.4.1 Clinical Implication of MSI; 3.5 CIMP; 3.5.1 Clinical Implications of CIMP; 3.6 Consensus Molecular Subtypes; References; Part II: Anatomic Considerations in Rectal Cancer Surgery; 4: Anatomical Basis of Rectal Cancer Surgery Focused on Pelvic Fascia; 4.1 Introduction; 4.2 Anatomic Concepts of Toldt Fascia; 4.3 Rectosacral and Waldeyer's Fascia Revisited |
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4.4 Dissection of Denonvilliers' Fascia Implicated in Total Mesorectal Excision4.5 In Conclusion; References; 5: The Lymphatic Spread of the Rectal Cancer; 5.1 Introduction; 5.2 The Pattern of the Lymphatic Drainage According to the Tumor Location; 5.3 Lymph Node Groups; 5.4 Concept of Lymphadenectomy; 5.5 Debated About Lateral Pelvic Lymph Node Dissection (West vs. East); 5.6 Selective Pelvic Lymph Node Dissection After Preoperative Chemoradiotherapy; 5.7 Pathologic Assessment of Rectal Lymph Node; References; 6: Anal Sphincter Complex Preservation; 6.1 Introduction; 6.2 Anatomy |
| Summary |
This book presents an Asian perspective on how the treatment of colorectal cancer can be optimized and standardized in ways that take into account technological advances and the trend towards individually tailored therapy. Readers will find careful, well-illustrated descriptions of the standard surgical techniques for rectal cancer and colon cancer that have contributed to recent improvements in 5-year survival rates in the Asia-Pacific region, where the incidence of colorectal cancer has been rising alarmingly due to lifestyle changes. The vital role now being played by minimally invasive laparoscopic and robotic options receives detailed scrutiny. Extent and timing of surgery, patient safety, risk of complications, and unresolved issues are all discussed. Furthermore, the use of surgery within the context of multimodal management including chemotherapy and radiotherapy is explained and an integrated approach for stage IV and recurrent disease is described. The book will serve as a valuable reference for young surgeons who are in training, experienced practitioners who want to enhance their knowledge and skills, and all others who wish to learn about this field |
| Bibliography |
Includes bibliographical references |
| Notes |
Restricted: Printing from this resource is governed by The Legal Deposit Libraries (Non-Print Works) Regulations (UK) and UK copyright law currently in force. WlAbNL |
| Subject |
Colon (Anatomy) -- Cancer -- Surgery
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Rectum -- Cancer -- Surgery
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Oncology.
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Cancer -- Surgery.
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Colorectal Neoplasms -- surgery
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Medical Oncology
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HEALTH & FITNESS -- Diseases -- General.
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MEDICAL -- Clinical Medicine.
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MEDICAL -- Diseases.
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MEDICAL -- Evidence-Based Medicine.
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MEDICAL -- Internal Medicine.
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Colon (Anatomy) -- Cancer -- Surgery
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Rectum -- Cancer -- Surgery
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| Form |
Electronic book
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| Author |
Kim, Nam Kyu, editor
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Sugihara, Kenichi, editor
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Liang, Jin-Tung, editor
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| LC no. |
2018937083 |
| ISBN |
9789811051432 |
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9811051437 |
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