| Description |
1 online resource |
| Contents |
Intro -- Foundations of Colorectal Cancer -- Copyright -- Contents -- Contributors -- Editor's note -- References -- Prologue -- Acknowledgments -- Section A: Epidemiological studies in CRC -- Chapter 1: Incidence and mortality of CRC -- Incidence -- Mortality -- Discussion -- References -- Chapter 2: Prognosis and follow-up of CRC patients: Role of diagnostic and therapeutic delay -- Survival and prognosis -- Follow-up strategies -- Quality of life and long-term sequelae -- Impact of diagnostic and therapeutic delay on stage and prognosis -- References -- Section B: Clinical manifestations and disease detection -- Chapter 3: Primary prevention of CRC -- Introduction -- Epidemiology and CRC -- Environment and CRC -- Diet -- Foods recommended to be reduced -- Processed and red meat -- Food and drink recommended to be increased -- Dairy products -- Dietary fiber and whole grain cereals -- Fish -- White and lean meat -- Coffee -- Garlic -- Lifestyle behaviors -- Unhealthy practices -- Excessive alcohol consumption -- Smoking -- Obesity -- Healthy practices -- Physical exercise -- Therapeutic strategies linked to lowering CRC risk -- Salicylic acetyl acid (SAA) -- Nonsteroidal antiinflammatory drugs (NSAIDs) -- Calcium and magnesium supplementation -- Calcium -- Magnesium -- Vitamin D supplementation -- B-group vitamins -- Folic acid and folate -- Antioxidants -- Hormone replacement therapy -- Statins -- Bisphosphonates -- Metformin -- Chondroitin sulfate and glucosamine -- Angiotensin II inhibitors -- Dietary patterns and CRC -- Relationship between dietary index and CRC -- Summary: Evidence and recommendations -- References -- Chapter 4: Early onset of CRC -- Introduction -- Exposure to environmental factors -- Microbiota alteration -- Hereditary factors -- Molecular differences -- Clinical features -- Conclusions -- References |
|
Chapter 5: Population-based universal screening for CRC: Secondary prevention -- Secondary prevention and screening concept -- Conditions for population screening: WHO general principles -- Colorectal cancer screening -- Colorectal cancer screening tests -- Colonoscopy -- Flexible sigmoidoscopy -- CT scan colonography -- Fecal occult blood test (FOBT) -- Other noninvasive tests: Stool or blood tests -- Requirements for the implementation of a screening program -- Evaluation of screening programs for their implementation: Efficacy, effectiveness, and efficiency -- Problems related to a colorectal cancer screening program -- Situation of screening in Spain -- Implementation of CRC screening in Spain -- Current situation of CRC screening in Spain: Cancer screening program network, 2019 -- Current situation of CRC screening in Galicia: Xunta de Galicia, 2019 -- Strengths and areas for improvement in Spanish screening programs -- References -- Chapter 6: The role of primary care in early referral of CRC patients -- The role of primary care in the early release of patients with CRC7,8 -- Prevention and promotion of health9, 10 -- Early diagnosis11 -- Symptomatology in colorectal cancer -- Changes in the usual way of making depositions -- Tests for early detection of colorectal cancer -- The guideline includes -- Stool occult blood test -- Sigmoidoscopy -- Colonoscopy -- Indications -- Preparation for tests -- Technique of performing a colonoscopy -- Evaluation of results -- Normal colonoscopy -- Polyp detection on colonoscopy14, 15 -- Monitoring of index or precursor injuries (polyps) -- Surveillance in special situations -- Criteria for referral to specialized care -- CRC of family/hereditary characteristics16, 17 -- References -- Chapter 7: Rapid diagnostic pathways for patients with suspected CRC -- Clinical pathways |
|
Rapid diagnosis pathways for colorectal cancer -- Introduction -- Implementation -- Published research -- Meeting referral criteria -- Cancer detection rates -- Percentages of diagnosed cancer cases -- Are RDPs sensitive and specific? -- Effect on care timing -- Effect on tumor stage and survival -- Possibilities for increasing effectiveness of CRC rapid pathways -- Conclusions -- References -- Section C: Diagnosis and staging -- Section C.I: Current diagnosis methods in colorectan cancer -- Chapter 8: Colon capsule endoscopy -- Introduction -- Technical characteristics of the second-generation colon capsule -- Preparation of the patient -- Comparative studies between colon capsule endoscopy and colonoscopy -- Comparative studies between CCE and colonography by computerized axial tomography -- Current indications and contraindications of the colon capsule endoscopy: Future perspectives -- Conclusions -- References -- Chapter 9: Endoscopic ultrasound in CRC -- Outline of technique -- EUS for rectal cancer staging -- Degree of invasion of intestinal wall (uT) -- Affectation of local adenopathies (uN) -- Significance of the circumferential resection margin -- EUS for assessment of neoadjuvant therapy response -- Interventional EUS -- EUS-FNA initial diagnosis and recurrence -- Differential diagnosis and diagnosis of neoplastic affectation of adenopathies -- Diagnosing tumor recurrence -- Drainage of postsurgical fluid collections -- Extrahepatic bile duct drainage -- Conclusion -- References -- Chapter 10: CT-Colonography (CTC): Technical requirements, indications and current status -- Introduction -- Technical requirements -- Preparation of the colon -- Distension of the colon -- Image acquisition -- Software and tools -- Indications for virtual colonoscopy -- Clinically significant findings in CTC -- Polyps -- Cancers -- Submucosal lesions |
|
Chronic diverticular disease -- Other -- Conclusions -- References -- Chapter 11: Rectal pathology: Findings at CT-Colonography -- Introduction -- Technical considerations -- Rectal pathology -- Polyps -- Villous tumors -- Malignant neoplasms -- Submucosal lesions -- Vascular lesions -- Internal hemorrhoids -- Rectal varices -- Venous malformations -- Hypertrophied anal papilla -- Inflammatory conditions -- Postoperative changes -- Pseudolesions and artifacts -- Other lesions -- Conclusion -- References -- Chapter 12: Applications of [18F] FDG PET and PET/CT in colorectal carcinoma -- Introduction -- Staging -- Restaging -- Recurrent disease detection -- Preoperative evaluation of potentially resectable disease -- Others: Incidental diagnosis of colorectal cancer. Assessment of treatment response -- Incidental diagnosis of colorectal cancer -- Assessment of treatment response -- New perspectives -- References -- Chapter 13: Magnetic resonance imaging (MRI) in staging and restaging after neoadjuvant therapy -- Introduction -- Total mesorectal excision -- Key anatomical references -- Mesorectal fascia and anterior peritoneal reflection -- Upper rectum -- Middle rectum -- Lower rectum -- Lymph nodes -- Local staging -- T-staging -- T1 and T2 tumors -- T3 tumors -- T4 tumors -- N-staging -- Restaging after neoadjuvant treatment -- T-restaging -- N-restaging -- The structured radiology report -- Location -- Morphology -- T-staging -- Extramural extension of the tumor -- Distance to mesorectal fascia -- Adenopathies and mesorectal tumor deposits -- Extramesorectal adenopathies -- Restaging after neoadjuvant treatment -- Locoregional recurrence -- References -- Chapter 14: Histopathological diagnosis of CRC -- Introduction -- Histopathological diagnosis of CRC in biopsies and endoscopic polypectomies |
|
Anatomopathological diagnosis of CRC in surgical specimens -- Histopathological types of colorectal neoplasms -- Biomarkers in CRC -- References -- Chapter 15: Colonoscopy: Technique and quality factors -- Historical introduction -- Colorectal cancer -- Colonoscopy technique -- Endoscopic description -- Magnification techniques -- Classification of colorectal polyps -- Serrated pathway in CRC -- Colonoscopy in the diagnosis of CRC in medium-risk populations -- Colonoscopy in the diagnosis of CRC in high-risk populations -- Colonoscopy quality indicators -- Endoscopic iconography -- References -- Chapter 16: Endoscopic diagnosis of preneoplastic and neoplastic lesions -- Introduction -- Identification of lesions -- Quality of colonoscopy -- High-definition colonoscopy -- Conventional chromoendoscopy -- Virtual chromoendoscopy -- Use of ancillary equipment and new colonoscopes -- Characterization of lesions -- Morphological evaluation -- Evaluation of the glandular pattern -- Kudos classification -- NICE classification -- WASP classification -- Role of colonoscopy in the diagnostic of advanced colonic lesions -- References -- Chapter 17: Oligometastatic disease -- References -- Chapter 18: Hereditary nonpolyposis CRC -- Introduction -- Genetic basis -- Molecular identification of Lynch syndrome -- Microsatellite instability analysis -- Immunohistochemistry for reparative proteins in tumor tissue -- Hypermethylation of MLH1 -- Detection of germline mutations in genomic DNA -- Clinical features -- Diagnosis of Lynch syndrome (HNPCC) and criteria for referral to a genetic counseling unit (GCU) -- Molecular study strategy -- Predictive models -- Clinical controls and surveillance -- Follow-up of healthy individuals in families with HNPCC -- Colorectal cancer screening -- Endometrial and ovarian cancer screening -- Control of other neoplasms |
| Subject |
Colon (Anatomy) -- Cancer.
|
|
Rectum -- Cancer.
|
|
Colon (Anatomy) -- Cancer
|
|
Rectum -- Cancer
|
| Form |
Electronic book
|
| Author |
Sierra, Alejandro Pazos
|
| ISBN |
9780323885713 |
|
0323885713 |
|
