| Description |
1 online resource (xxviii, 1166 pages : illustrations (chiefly color)) |
| Series |
Biomarkers in disease |
|
Biomarkers in disease.
|
| Contents |
Part I Single Components -- Soluble Guanylyl Cyclase Alpha1 Subunit as a Biomarker of Toxicity: Applications to Investigate Endocrine-Disrupting Chemicals -- Serum Paraoxonase 1 as a Biomarker in Toxicology -- Erythrocyte Acetylcholinesterase as a Biomarker of Environmental Lead Exposure -- Fortilin as a Biomarker in Toxicity -- Antibodies as Biomarkers: Effect of Microcystin Exposure -- Gamma-H2AX Expression as a Biomarker of Carcinogenesis: Applications to Toxicology -- The Carcinogen Glycidol and Use of N-(2,3-Dihydroxypropyl)-valine in Hemoglobin as a Biomarker of Exposure -- Biomarkers of Antibiotic Toxicity: A Focus on Metronidazole -- Part II Panels and Arrays -- Pro-inflammatory Markers of Environmental Toxicants -- Oxidative Stress Biomarkers and Their Applications to Detect Excessive Fluorine -- Biomarkers of Alcohol Toxicity -- Biomarkers of Liver Injury due to Toxic Agents: Progress, Current Applications, and Emerging Directions -- Biomarkers for Assessing Mycotoxin Exposure and Health Effects -- Metabolomics Profiling of Di-(2-propylheptyl) Phthalate (DPHP) Biotransformation Products as Exposure Markers: Analytical Strategy and Application -- Biomarkers of Neurotoxicity -- Part III Genetic, Cellular, and Histological Variables -- Genetic and Epigenetic Biomarkers Related to 2-Oxoglutarate/Fe(II)-Dependent Oxygenases and Implications for Disease and Toxicology -- DNA Adducts as Biomarkers in Toxicology -- DNA Methylation as a Biomarker and Application to Aluminum: ADRB2 50-Untranslated Region (50-UTR) Methylation Level -- Autophagy as a Biomarker of Cytotoxicity -- Erythrocyte Glutathione Transferase P1-1 as a Biomarker in Environmental Toxicology: A New Narrative -- Extracellular MicroRNAs as Putative Biomarkers of Air Pollution Exposure -- Endothelial Extracellular Vesicles as Biomarkers of Toxic Molecules -- Part IV Functional and Physiological Variables and Platforms -- Biomarkers of Lead Exposure: Platforms and Analysis -- Murine Embryonic Stem Cells as Platform for Toxicity Studies: Use of Human Survivin Promoter with Green Fluorescent Protein Reporter for High-Throughput Screening -- LC-MS-Based Metabolomics in the Identification of Biomarkers Pertaining to Drug Toxicity: A New Narrative -- Bovine Whole Blood Cells as a Biomarker Platform for Biological Toxicology: A Focus on Thiacloprid -- Blood-Brain Barrier Function as a Biomarker in Toxicology: Impact of Environmental Toxicants -- Anogenital Distance: Features, Measures, and Uses as a Biomarker for Toxicity In Utero -- Micronucleus Assay in Lymphocytes for Human Biomonitoring and Clinical Studies -- Salivary Biomarkers in Toxicology: An Update Narrative -- Part V Biomarkers in Specific Conditions or Scenarios -- Doxorubicin Cardiotoxicity: Preclinical and Clinical Circulating Protein Markers -- Biomarkers of Sulfur Mustard (Mustard Gas) in Urine -- Biomarkers of Cardiopulmonary Injury and Impact of Bromine Toxicity -- Biomarkers of PM 2.5 Exposure: Use of Metabolomics as a Platform -- Sunscreens: Toxic Effects as Determined by Biomarkers -- Drug-Induced Nephrotoxicity and Use of Biomarkers -- Biomarkers of Tobacco Use: Relevance to Tobacco Harm Reduction -- Bleaching Agents as Toxic Compounds and Biomarkers of Damage -- Endocrine Disruptors and Markers of Anthropogenic Activity: A Risk for Water Supply and Health -- Biomarkers in the Biomonitoring of Fluoride Toxicity: An Overview -- New Approaches to Evaluate the Cytotoxic Potential of Leishmanicidal Drugs Using Human Peripheral Blood -- Contrast-Induced Nephropathy (CIN) and Biomarkers -- Lead and Aquatic Ecosystems, Biomarkers, and Implications for Humankind -- Per- and Polyfluoroalkyl Substances (PFAS) and Their Toxicology as Evidenced Through Disease and Biomarkers -- The Complement System as a Biomarker of Environmental Pollutants as Toxic Agents: A Focus on Polybrominated Diphenyl Ethers (PBDEs) Exposure -- Biomarkers of the Toxic Effects of Chemotherapeutic Agents: A Focus on Antimalarials -- Part VI Biomarkers in Models and Modeling Toxicity -- Linking Arsenic, DNA Methylation Biomarkers, and Transgenerational Neurotoxicity: Modeling in Zebrafish -- Modeling with Biomarkers: Nitrosamines and Phytochemical Protection -- Different Mice Strains in Biomarker Responses to Toxic Agents: The Example of Acetaminophen -- Part VII Resources -- Recommended Resources for Biomarkers in Disease: Toxicology |
| Summary |
This handbook of the series Biomarkers in Disease informs comprehensively about all aspects of monitoring and detecting toxicity in the human body and model organisms. Biomarkers for assessing toxicity in diverse organs are presented and different assays and methods are explained. Single compounds and drugs and their toxicity for humans are shown and the methods for detection described. Similar to all the volumes of the Biomarkers in Disease series, the chapters are written by experts in their field, each chapter features key facts summarizing the most important aspects of its respective topic and the definitions of words and terms facilitate the reading and understanding. This handbook is a must-have for researchers in toxicology and biomedicine who analyze the effects of drugs and various other substances in the human body and in model organisms. It also serves as a thorough guide for clinicians and pharmacologists |
| Notes |
Includes index |
|
Print version record |
| Subject |
Toxicology.
|
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Biochemical markers.
|
|
Toxicology
|
|
Biomarkers
|
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toxicology.
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Biochemical markers
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Toxicology
|
| Genre/Form |
Electronic books
|
| Form |
Electronic book
|
| Author |
Patel, Vinood B., editor.
|
|
Preedy, Victor R., editor.
|
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Rajendram, Rajkumar, editor.
|
| ISBN |
9783031073922 |
|
3031073924 |
|
