| Description |
1 online resource |
| Series |
Cancer Etiology, Diagnosis and Treatments |
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Cancer etiology, diagnosis, and treatments.
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| Contents |
Preface; Bidirectional Crosstalk between Estrogen Signaling Pathways and DNA Repair Machinery; Abstract; Introduction; Milestones on the Route Leading to the Recognition of Correlation between Hormonal Signaling and Genomic Stability; Age and Gender Related Differences in the Prevalence of Oral Cancer Suggest a Crucial Role of Defective Female Hormal Mechanism in Cancer Risk; Increased Female to Male Ratio of Excessive Cancer Risk in Northen Geographic Regions Is in Correlation with Darkness Related Femal Hormonal Deficiency |
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Defective Estrogen Signaling Induces Insulin Resistance and Its Comorbidities: Cardiovascular Diseases and MalignanciesBidirectional Crosstalk between Estrogen Signaling Pathways and DNA Repair Machinery; Mutual Upregulation between Estrogen Receptor Signaling and DNA Controlling Activity of BRCA-Protein; Estrogen Signaling Promotes the Expression and Activity of Tumor Suppressor p53 Gene; Interplay between Estrogen Signaling and PTEN during Cell Proliferation; PALB2 Protein Has Important Role in Genome Stabilization in Strong Correlation with BRCA Proteins |
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Crosstalk between Estrogen Signaling and other Hormonal Mechanisms for the Upregulation of Genome Stabilizer MachineryAntiestrogen Use Is a Medical Mistake; Molecular Mechanisms of the Transient Upregulation of Estrogen Signaling by Antiextrogen Treatment; Conclusion; References; Regucalcin Plays a Crucial Role as a Suppressor in Carcinogenesis; Abstract; Introduction; Suppressive Role of Regucalcin in Cell Proliferation; Regucalcin Suppresses Manifold Pathways of Cell Signaling; Regucalcin Suppresses Cell Proliferation; Suppressive Role of Regucalcin in Carcinogenesis of Animal Models |
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Regucalcin Is Involved in the Depression of Liver RegenerationInvolvement of Regucalcin in Human Hepatocarcinogenesis; Involvement of Reguclcin in Various Human Cancers; Regucalcin Gene Expression Is Suppressed in Various Cancer Tissues; Involvement of Regucalcin in Lung Cancer Cells; Involvement of Regucalcin in Breast Cancer Cells; Involvement of Regucalcin in Prostate Cancer Cells; Involvement of Regucalcin in Kidney Cancer Cells; Involvement of Regucalcin in Pancreatic Cancer Cells; Higher Regucalcin Gene Expression Prolongs Survival of Cancer Patients; Prospect; References |
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Alternative Way to Inhibit STAT3 Signaling in Gastric CancerAbstract; Introduction; STAT3 Signaling in Gastric Cancer; STAT3 Inhibition in Gastric Cancer; ; Current State and Limitations; SHP-1: A Promising Phosphatase to Inactivate STAT3; Induction of SHP-1 to Inhibit STAT3 Signaling; Future Perspectives; Conclusion; References; Colorectal Cancer in Patients with Inflammatory Bowel Disease; Abstract; Introduction; Epidemiology; Risk of CRC in CD; Risk of CRC in UC; Mortality of CRC in IBD; Risk Factors for CRC in IBD Patients; Age at Onset of IBD; Disease Extent; Duration of Disease |
| Bibliography |
Includes bibliographical references and index |
| Notes |
Description based on print version record |
| Subject |
Carcinogenesis.
|
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Carcinogenesis
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HEALTH & FITNESS -- Diseases -- General.
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MEDICAL -- Clinical Medicine.
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MEDICAL -- Diseases.
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MEDICAL -- Evidence-Based Medicine.
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MEDICAL -- Internal Medicine.
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Carcinogenesis
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| Form |
Electronic book
|
| Author |
Yamaguchi, Masayoshi, editor
|
| LC no. |
2020677239 |
| ISBN |
9781536104455 |
|
1536104450 |
|
