| Description |
1 online resource |
| Series |
Smart nanomaterials technology |
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Smart nanomaterials technology
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| Contents |
Intro -- Preface -- Contents -- About the Editors -- Smart Nanotechnology in Pathological Hypoxia: An Innovative Avenue for a Clinical Hurdle -- 1 Introduction -- 1.1 Molecular Responses to Hypoxia-Hypoxia-Inducible Factors and Allied Pathways -- 2 Smart Nanomaterials -- 2.1 Smart Nanomaterials Targeting Hypoxic Tissues -- References -- Bioinspired Nanosystems Interacting with the Host Environment: Smart Nanosystems -- 1 Introduction -- 2 Smart Nanosystems in Drug Delivery -- 3 Targeted Drug Delivery Approaches -- 4 Bioinspired Nanocarriers -- 4.1 Lipid Nanostructures |
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4.2 Lipid Nanoparticles (LNPs) -- 4.3 Lipid Nanocapsules (LNCs) -- 4.4 Lipid-Based Micelles -- 4.5 Viral Vectors -- 4.6 Liposome-Based Nanocarriers -- 4.7 Polymeric Nanocarrier -- 5 Nanorobotics -- 5.1 Targeted Motion -- 5.2 Drug Release Mechanism -- 6 Potential and Limitations of Smart Nanosystem -- 7 Conclusion -- References -- Nanotechnology-Based Approaches to Relieve Tumour Microenvironment Hypoxia via Enhanced Oxygen Delivery -- 1 Introduction -- 2 Nanotechnology-Based Approaches for O2 Delivery in Hypoxic Site -- 2.1 Nanochemical Decomposition for O2 Release |
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2.2 Breakdown of Catalase to Generate O2 -- 2.3 Water-Based Splitting to Produce O2 -- 3 Various Strategically Used Nanomaterials for TME Hypoxia -- 3.1 PFC-Based Oxygen Carriers (PFOCs) and Fe2+ Porphyrin Systems -- 3.2 Artificial Red Blood Cells Substitute (RBCSs) -- 3.3 Metal-Organic Framework (MOFs) -- 3.4 Oxygen Microcapsules -- 4 Nanotechnology-Based Therapeutic Approaches for Hypoxia -- 4.1 Nanoparticles Conquering Hypoxia-Inducing Factor -- 4.2 Targeting Metastatic Hypoxic Condition by Nanodelivery Against Chemoresistance |
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4.3 Nanoparticle Relieving: Lowering Hypoxic TME by Immunotherapy -- 5 Conclusion -- References -- Recent Progress in Hypoxia-Targeting: Peptide-Based Nanomaterials -- 1 Introduction -- 2 Polypeptide-Based Nanoparticles -- 3 Self-Assembled Peptide-Based Nanoparticles -- 4 Peptide and Polymer Conjugate Nanoparticles -- 5 Peptide-Functionalized Liposomes -- 6 Polysaccharides Functionalization Study by Peptides -- 7 Conclusion and Outlook for the Future -- References -- Recent Advancements in the Field of Stimuli-Responsive Polymeric Nanomaterials for Cancer Treatment -- 1 Introduction |
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2 Smart Polymeric Nanobiomaterials -- 2.1 The Preparation Process of Stimuli-Responsive Polymers -- 3 Physicochemical Characterization -- 3.1 Single Stimuli-Responsive Smart Materials -- 3.2 Dual Stimuli-Responsive Smart Materials -- 3.3 Multi-stimuli-Responsive Smart Materials -- 4 Anti-tumor Efficiency of Stimuli-Responsive Nanopolymers -- 4.1 Single Stimuli-Responsive Smart Materials -- 4.2 Dual Stimuli-Responsive Smart Materials -- 4.3 Multi-stimuli-Responsive Smart Materials -- 5 Conclusion -- References |
| Summary |
The book showcases the newest research on smart nanoplatforms responding to hypoxia; an omnipresent pathological feature of many modern-day diseases and its potential applications. The book demonstrates the versatility of hypoxia targeted smart nanoplatforms in disease management in diverse pathological settings presented in chapters contributed by various experts in the field. The themes in the book touch upon critical facets to address pathological hypoxia such as nanomaterials enhancing oxygenation, hypoxia responsive nanoformulations which deliver the drug directly to the hypoxic site, limited toxicity and enhanced efficacy of smart nanoformulations to counter molecular consequences of hypoxia, and theranostics combining hypoxia detection systems with drug delivery systems. This book disseminates the current implications of smart nanomaterials in disease management that can be exploited by scholars, researchers, and pharma industries to develop, manufacture, and commercialize hypoxia targeted diagnostics and therapeutics |
| Notes |
Online resource; title from PDF title page (SpringerLink, viewed July 11, 2023) |
| Subject |
Nanostructured materials.
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Smart materials.
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Nanostructured materials
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Smart materials
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| Form |
Electronic book
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| Author |
Chawla, Sonam
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Singh, Sachidanand.
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Husen, Azamal.
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| ISBN |
9789819917181 |
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9819917182 |
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