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Book Cover
E-book
Author Burstein, Harold J

Title Targeted therapies in breast cancer / Harold J. Burstein
Published Oxford ; New York : Oxford University Press, ©2011

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Description 1 online resource (54 pages) : illustrations
Series Oxford American pocket notes
Oxford American pocket notes.
Contents Cover; Table of Contents; Introduction; Antiestrogen Therapies; Aromatase Inhibitors (AI's); Selective Estrogen Receptor Modulators (SERM's) and Estrogen-Receptor Downregulators (ERD's); Chemotherapeutic Agents-Microtubule Targeting Agents; Taxanes; Ixabepilone; Eribulin Mesylate; HER2 Directed Therapies for Metastatic Breast Cancer; Trastuzumab; Trastuzumab-Refactory Breast Cancer; Investigational Agents; HER2 Directed Therapy for Early Stage Breast Cancer; Angiogenesis Inhibitors in Breast Cancer; Bevacizumab; VEGFR Inhibitors; PARP Inhibitors; Emerging Areas; References
Summary The development of monoclonal antibodies and other inhibitors of specific molecules, fully utilizing the insights learned from molecular techniques such as comparative microarrays and protein expression patterns, has led to the development and FDA approval of several agents for the treatment of breast cancer, such as trastuzamab (Herceptin, targeting HER-2 positive tumors) and lapatinib (Tykerb, targeting tumors with mutated/overexpressed EGFR 1 and 2). Other agents specifically targeting the estrogen receptor, the aromatose pathway and microtubule dynamics, fulvestrant (Faslodex, targeting th
Bibliography Includes bibliographical references
Notes English
Print version record
Subject Breast -- Cancer -- Treatment -- Handbooks, manuals, etc
Drug targeting -- Handbooks, manuals, etc
Drug Delivery Systems
Breast Neoplasms -- drug therapy
HEALTH & FITNESS -- Diseases -- Cancer.
MEDICAL -- Oncology.
Breast -- Cancer -- Treatment
Drug targeting
Genre/Form Handbooks and manuals
Form Electronic book
LC no. 2012419417
ISBN 9780199749751
0199749752
1280699094
9781280699092
9786613676061
6613676063