Title Modern keratoplasty surgical techniques and indications / Jorge L. Alió, Jorge L. Alió del Barrio, editors

Published Cham : Springer, 2023

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Description 1 online resource (521 p.) Series Essentials in ophthalmology Essentials in ophthalmology. Contents Intro -- Preface -- Preface -- References -- Acknowledgments -- Contents -- 1: Introduction: Current Status of Modern Corneal Transplantation-Success, Failures and Turning Points -- Introduction -- Modern Modalities of Corneal Transplantations -- Success, Failures and Complications of Modern Corneal Transplants -- Complications of Corneal Transplants That Affect the Outcome -- Graft Failure Modalities -- Ad. 1. Frequency and Main Causes of Corneal Graft Anatomical Failure -- Anatomical Failure in the Different Types of Corneal Grafts -- Penetrating Keratoplasty Deep Anterior Lamellar Keratoplasty -- Endothelial Keratoplasty -- Ad. 2 -- Functional Outcomes of Corneal Graft Procedures -- Anatomical Outcomes After Regraft -- Functional Outcomes After Regraft -- Survival Rate of Corneal Graft -- Conclusion: Real Success Rate of Modern Corneal Transplantation Procedures -- References -- Suggested Reading -- Part I: Preparing the Patient -- 2: Modern Eye Banking: Preservation, Type of Tissues, and Selection -- Introduction -- Donor's Screening and Tissue Collection -- Preservation Techniques -- Moist Chamber Preservation -- Cryopreservation Hypothermic Storage -- Organ Culture Preservation -- Type of Tissues -- Penetrating Keratoplasty -- Anterior Lamellar Keratoplasties -- Posterior Lamellar Keratoplasties -- Prestripped, Precut and Preloaded Tissues in Eye Banks -- Amniotic Membrane and Scleral Patches -- Tissue Selection -- Microbiological Testing -- Morphological Examination: Slit-Lamp Biomicroscopy -- Endothelial Evaluation: Inverted Light or Specular Microscopy -- Sterile Donor Tomography -- Detection of Cornea Guttata in the Eye Bank Benefits of a Highly-Structured Quality Management System (QMS) by Example of the LIONS Eye Bank Saar-Lor-Lux, Trier/Westpfalz -- Future Perspectives -- References -- 3: Risk Classification and Management of Corneal Grafts, Human Leukocyte Antigen Matching, and Options for Immunosuppression Therapy -- Introduction -- Risk Stratification -- Risk Factors -- Primary Diagnosis -- Previous Transplantation -- Glaucoma -- Active Inflammation -- Herpetic Infection -- Neovascularization -- Atopy -- Aphakia -- Age -- Limbal Stem Cell Deficiency -- Additional Factors Mitigation Strategies for Corneal Graft Rejection -- Role of Lymphangiogenesis -- Anti-angiogenic and Lymphangiogenic Therapy -- Histocompatibility Matching -- Strategies for Immunosuppression -- Topical Therapy -- Steroids -- Cyclosporine -- Tacrolimus -- Systemic Therapy -- Cyclosporine -- Mycophenolate -- Mycophenolate vs. Cyclosporine -- Tacrolimus -- Selecting Immunosuppression According to Risk Stratification -- Special Considerations for Limbal Stem Cell Transplantation -- Conclusion -- References -- Untitled Summary Keratoplasty techniques have evolved in the last 15 years into a variety of forms, which have diversified the previous monographic presence of the penetrating keratoplasty technique. The development of anterior lamellar graft (DALK), and posterior lamellar graft (DSAEK), makes an important change in the approach to lamellar surgery. Later on, the appearance of DMEK and superficial lamellar keratectomy broadened the spectrum. Today, intralamellar surgery has evolved with a number of techniques that involve stromal enhancement with biologically active or acellular corneal laminas from donors, customized lenticles from SMILE surgeries or customized by corneal topography, and more recently, corneal regeneration of the stroma by advanced techniques using mesenchymal stem cells. This book offers a comprehensive overview of modern keratoplasty techniques, the technology, surgical skills, and outcomes. It highlights the practical uses of keratoplasty for all cornea surgeons and anterior segment surgeons. The book is divided into sections, each covering a specific type of keratoplasty, including chapters on innovations within each surgery type. The goal of this book is to unify all recent knowledge about the different keratoplasty techniques and outcomes, creating a one-stop resource for ophthalmaolgy surgeons. Modern Keratoplasty is a must-have resource for corneal specialists and surgeons, anterior segment surgeons, refractive surgeons, cataract surgeons, residents, fellows, and corneal researchers Notes 4: Management of the Vascularized Cornea Before Corneal Graft Surgery: Fine-Needle Diathermy and Inhibition of VEGF Includes index Online resource; title from PDF title page (SpringerLink, viewed October 12, 2023) Subject Cornea -- Surgery. Cornea -- Surgery Form Electronic book Author Alió, Jorge L. Barrio, Jorge L. Alió del. ISBN 9783031324086 3031324080

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