Description |
1 online resource (x, 274 pages) : illustrations (some color) |
Series |
Methods in molecular biology, 1940-6029 ; 1872 |
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Methods in molecular biology (Clifton, N.J.) ; v. 1872. 1064-3745
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Contents |
880-01 Intro; Preface; Contents; Contributors; Chapter 1: An Introduction to Drug Testing: The Expanding Role of Mass Spectrometry; 1 Introduction; 2 Therapeutic Drug Monitoring; 3 Toxicology; 4 Evaluation of Methods; 5 Quality Assurance; 6 Conclusions; References; Chapter 2: Quantification of Eight Cannabinoids Including Cannabidiol in Human Urine Via Liquid Chromatography Tandem Mass Spe ... ; 1 Introduction; 2 Materials; 2.1 Supplies and Equipment; 2.2 Cannabinoid Calibrator and Quality Control Solutions; 2.3 Solutions and Buffers; 3 Methods; 3.1 Sample Preparation |
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880-01/(S Introduction to drug testing : the expanding role of mass spectrometry / Christine L.H. Snozek, Loralie J. Langman, and Steven W. Cotten -- Quantification of eight cannabinoids Including cannabidiol in human urine via liquid chromatography tandem mass spectrometry / Karl B. Scheidweiler and Allan J. Barnes -- Analysis of benzodiazepines for drug-facilitated assaults and abuse settings (urine) / Olaf H. Drummer, Matthew Di Rago, and Dimitri Gerostamoulos -- Targeted opioid screening assay for pain management using high-resolution mass spectrometry / Darlington Danso, Loralie J. Langman, and Paul J. Jannetto -- Measurement of buprenorphine and norbuprenorphine in urine / Andrea R. Terrell, Vipin Adhlakha, and Poluru Reddy -- Quantitation of tapentadol by liquid chromatography : tandem mass spectrometry / Graham R. Jones and Russell P. Handy -- Therapeutic drug monitoring of lacosamide by LC-MS/MS / He Sarina Yang and Leslie Edinboro -- LC-MS/MS method for the quantification of the leflunomide metabolite, teriflunomide, in human serum/plasma / Geoffrey S. Rule, Alan L. Rockwood, and Kamisha L. Johnson-Davis -- Analysis of tryptic peptides from therapeutic monoclonal antibodies using LC-MS/MS / Maria Alice V. Willrich -- Quantification of methotrexate in human serum and plasma by liquid chromatography tandem mass spectrometry / Gabrielle N. Winston-McPherson, Michael Schmeling, and Andrew N. Hoofnagle -- Simultaneous determination of tacrolimus and cyclosporine A in whole blood by ultrafast LC-MS/MS / Matthew W. Bjergum, Paul J. Jannetto, and Loralie J. Langman -- Liquid chromatography-tandem mass spectrometry (LC-MS/MS) method to quantify gabapentin and pregabalin in urine / Stephen Merrigan and Kamisha L. Johnson-Davis -- Evolving landscape of designer drugs / Sherri L. Kacinko and Donna M. Papsun -- Analysis of synthetic cannabinoid metabolites by liquid chromatography-tandem mass spectrometry / Gregory C. Janis -- Quantification of designer opioids by liquid chromatography-tandem mass spectrometry / Sherri L. Kacinko and Joseph W. Homan -- Screening analysis for designer stimulants by LC-MS/MS / Piotr Adamowicz and Bogdan Tokarczyk -- Drug screening using liquid chromatography quadrupole time-of-flight (LC-QqTOF) mass spectrometry / Jennifer M. Colby and Kara L. Lynch -- Alternate matrices : meconium, cord tissue, hair, and orral fluid / Kendra L. Palmer and Matthew D. Krasowski -- Salt-assisted liquid-liquid extraction of meconium for analysis of cocaine and amphetamines by liquid chromatography-tandem mass spectrometry / Melissa M. Goggin and Gregory C. Janis -- Detection of in utero cannabis exposure in umbilical cord tissue by a sensitive liquid chromatography-tandem mass spectrometry method / Fang Wu, Triniti L. Jensen, and Gwendolyn A. McMillin -- Quantitation of ethyl-β-D-glucuronide in human umbilical cord tissue by liquid chromatography tandem mass spectrometry (LC-MS/MS) / Simuli L. Wabuyele and Gwendolyn A. McMillin -- Analysis of drugs in oral fluid using LC-MS/MS / Cynthia A. Coulter and Christine M. Moore -- Determination of cocaine and metabolites in dried blood spots by LC-MS/MS / Lars Ambach and Christophe Stove |
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3.2 Liquid Chromatography Tandem Mass Spectrometry Analysis4 Notes; References; Chapter 3: Analysis of Benzodiazepines for Drug-Facilitated Assaults and Abuse Settings (Urine); 1 Introduction; 1.1 Benzodiazepines and Their Analogs; 1.2 Overview of Published Methods; 2 Materials; 2.1 Solutions and Reagents (See Note 5); 2.2 Supplies and Equipment; 3 Methods; 3.1 Sample Analysis; 3.2 Analysis; 4 Notes; References; Chapter 4: Targeted Opioid Screening Assay for Pain Management Using High-Resolution Mass Spectrometry; 1 Introduction; 2 Materials; 2.1 Samples and Reagents |
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2.2 Standards and Controls2.3 Supplies and Equipment; 3 Methods; 3.1 Extraction Procedure (see Note 3); 3.2 Analysis; 4 Notes; References; Chapter 5: Measurement of Buprenorphine and Norbuprenorphine in Urine; 1 Introduction; 2 Materials; 2.1 Prepared Reagents (See Note 1); 2.2 Preparation of Urine Calibrators and Controls; 2.3 Supplies and Analytical Equipment; 3 Method; 3.1 Sample Preparation; 3.2 Analysis; 4 Notes; References; Chapter 6: Quantitation of Tapentadol by Liquid Chromatography: Tandem Mass Spectrometry; 1 Introduction; 2 Materials; 2.1 Solvents (See Note 1) |
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2.2 Supplies and Equipment3 Methods; 3.1 Preparation of Working Standards and Unknown Samples; 3.2 Analysis; 4 Notes; References; Chapter 7: Therapeutic Drug Monitoring of Lacosamide by LC-MS/MS; 1 Introduction; 2 Materials; 2.1 Internal Standard, Calibrators, Controls, and Buffers; 2.2 Supplies and Analytic Equipment; 3 Methods; 3.1 Extraction of Lacosamide from Plasma and Serum; 3.2 LC-MS/MS Analysis; 3.3 Data Analysis; 4 Notes; References; Chapter 8: LC-MS/MS Method for the Quantification of the Leflunomide Metabolite, Teriflunomide, in Human Serum/Plasma; 1 Introduction; 2 Materials |
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2.1 Supplies and Equipment2.2 Standards and Controls; 2.3 Solutions; 3 Methods; 3.1 Sample Preparation; 3.2 Analysis; 4 Notes; References; Chapter 9: Analysis of Tryptic Peptides from Therapeutic Monoclonal Antibodies Using LC-MS/MS; 1 Introduction; 1.1 Tryptic Peptide Methods; 2 Materials; 2.1 Reagents and Mobile Phases; 2.2 Standards and Controls; 2.3 Supplies and Instrumentation; 3 Methods; 3.1 Saturated Ammonium Sulfate Extraction; 3.2 Trypsin Digestion; 3.3 LC-MS/MS Set-Up and Quantitation of Infliximab; 4 Notes; References |
Bibliography |
Includes bibliographical references and index |
Notes |
Online resource; title from PDF title page (SpringerLink, viewed October 22, 2018) |
Subject |
Drugs -- Analysis -- Laboratory manuals
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Liquid chromatography.
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Mass spectrometry.
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Chromatography, Liquid -- methods
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Mass Spectrometry -- methods
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Drug Evaluation -- methods
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Pharmaceutical Preparations -- analysis
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Chromatography, Liquid
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Mass Spectrometry
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liquid chromatography.
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mass spectrometry.
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Pharmacology.
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Medical -- Pharmacology.
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Drugs -- Analysis
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Liquid chromatography
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Mass spectrometry
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Genre/Form |
Electronic books
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Laboratory manuals
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Laboratory manuals.
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Manuels de laboratoire.
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Form |
Electronic book
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Author |
Langman, Loralie J., editor.,
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Snozek, Christine L. H., editor
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ISBN |
9781493988235 |
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1493988239 |
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9781493988228 |
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1493988220 |
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