| Description |
1 online resource (354 p.) |
| Contents |
Intro -- The Neurobiology of Aging and Alzheimer Disease in Down Syndrome -- Copyright -- Dedication -- Contents -- Contributors -- Acknowledgments -- Chapter 1: Introduction -- History -- Prevalence of DS and phenotype -- People with DS are living longer -- The link between Alzheimer's disease and Down syndrome -- Overview of the chapters -- Chapter 2: Alzheimer's neuropathology in Down syndrome: From gestation to old age -- Introduction -- Prenatal brain pathology in DS -- Adult brain pathology in DS -- Cortical amyloid in AD and DS -- Cerebellar amyloid in AD and DS |
|
Single cell expression profiling in DS -- Summary -- Acknowledgments -- Chapter 3: The contribution of inflammation to Alzheimer's disease in Down syndrome -- Introduction -- Neuroinflammation in Alzheimer's disease -- Neuroinflammation in Down syndrome-Genetics -- Neuroinflammation in Down syndrome: Biomarker studies -- Neuroinflammation as a function of age and AD: Autopsy studies -- Drug development for AD with a focus on neuroinflammation -- Conclusions -- Chapter 4: The role of cerebrovascular disease in aging and Alzheimer's disease among people with Down syndrome -- Introduction |
| Notes |
Description based upon print version of record |
|
Biomarkers in neuron-derived exosomes in Down syndrome |
| Form |
Electronic book
|
| Author |
Lott, Ira
|
| ISBN |
9780128188460 |
|
0128188464 |
|
