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Title Endocrine disruption modeling / editor, James Devillers
Published Boca Raton : Taylor & Francis, 2009


Description 1 online resource (404 pages, 7 unnumbered pages of plates) : illustrations (some color)
Series QSAR in environmental and health sciences
QSAR in environmental and health sciences.
Contents In silico methods for modeling endocrine disruption / J. Devillers -- Mechanisms of endocrine disruptions : a tentative overview / Jean-Marc Porcher, James Devillers, and Nathalie Marchand-Geneste -- Population dynamics modeling : a tool for environmental risk assessment of endocrine disrupting chemicals / A.R. Brown [and others] -- Application of pharmacokinetic modeling to understand the mechanism of action of endocrine disrupting chemicals / James Devillers -- Comparative modeling review of nuclear hormone receptor superfamily / Nathalie Marchand-Geneste and James Devillers -- The FDA's endocrine disruptor knowledge base (EDKB) : lessons learned in QSAR modeling and applications / Weida Tong
A structure-activity relationship (SAR) analysis for the identification of environmental estrogens : the categorical-SAR (CAT-SAR) approach / Albert R. Cunningham -- Kohonen and counterpropagation neural networks employed for modeling endocrine disruptors / Marjana Novic and Marjan Vracko -- Quantitative spectrometric data-activity relationships (QSDAR) models of endocrine disruptor binding activities / Richard D. Beger -- Mechanism-based modeling of estrogen receptor binding affinity : a COREPA implementation / Ovanes Mekenyan and Rossitsa Serafimova -- Molecular field analysis methods for modeling endocrine disruptors / Jean-Pierre Doucet -- Structure-activity modeling of a diverse set of endrogen receptor ligands / J. Devillers [and others] -- SAR and QSAR analyses of substituted dibenzoylhydrazines for their mode of action as ecdysone agonists / Toshio Fujita -- e-Endocrine disrupting chemical databases for deriving SAR and QSAR models / Nathalie Marchand-Geneste [and others]
Summary Uses Computational Tools to Simulate Endocrine Disruption PhenomenaEndocrine Disruption Modeling provides a practical overview of the current approaches for modeling endocrine activity and the related potential adverse effects they may induce on environmental and human health. Based on the extensive research of an international panel of contributors from industry, academia, and regulatory agencies, this is the first book devoted to using computer tools to better understand and simulate the multifaceted aspects of endocrine disruption in humans and wildlife. Explores Diverse Modeling Techniques
Bibliography Includes bibliographical references and index
Subject Endocrine disrupting chemicals -- Research -- Methodology
QSAR (Biochemistry)
Quantitative Structure-Activity Relationship
MEDICAL -- Pharmacology.
QSAR (Biochemistry)
Form Electronic book
Author Devillers, James, 1956-
ISBN 9781420076363