An enzyme group that specifically dephosphorylates phosphotyrosyl residues in selected proteins. Together with PROTEIN-TYROSINE KINASE, it regulates tyrosine phosphorylation and dephosphorylation in cellular signal transduction and may play a role in cell growth control and carcinogenesis
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Protein-tyrosine phosphatase. : Protein tyrosine phosphatases : structure, signaling and drug discovery / Lalima G. Ahuja