Serum glycoprotein produced by activated MACROPHAGES and other mammalian MONONUCLEAR LEUKOCYTES. It has necrotizing activity against tumor cell lines and increases ability to reject tumor transplants. Also known as TNF-alpha, it is only 30% homologous to TNF-beta (LYMPHOTOXIN), but they share TNF RECEPTORS
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Infliximab. : Infliximab : pharmacology, uses and limitations / Antonio D. Medrano Acevedo and Montserrat Fajardo Gaitan, editors
2012
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Infliximab -- Therapeutic use : Infliximab : pharmacology, uses and limitations / Antonio D. Medrano Acevedo and Montserrat Fajardo Gaitan, editors