A class of lipoproteins of small size (4-13 nm) and dense (greater than 1.063 g/ml) particles. HDL lipoproteins, synthesized in the liver without a lipid core, accumulate cholesterol esters from peripheral tissues and transport them to the liver for re-utilization or elimination from the body (the reverse cholesterol transport). Their major protein component is APOLIPOPROTEIN A-I. HDL also shuttle APOLIPOPROTEINS C and APOLIPOPROTEINS E to and from triglyceride-rich lipoproteins during their catabolism. HDL plasma level has been inversely correlated with the risk of cardiovascular diseases
High density lipoproteins -- Congresses. : High density lipoproteins and atherosclerosis : proceedings of the Third Argenteuil Symposium held under the auspices of the Fondation cardiologique Princesse Liliane in Waterloo, Belgium on November 7-8, 1977 / editors, A. M. Gotto, Jr., N. E. Miller, M. F. Oliver