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Title Translational cardiology : molecular basis of cardiac metabolism, cardiac remodeling, translational therapies and imaging techniques / Cam Patterson, Monte S. Willis, editors
Published New York : Humana Press, ©2012


Description 1 online resource : illustrations (some color)
Series Molecular and translational medicine
Molecular and translational medicine
Contents Relationship Between Myocardial Ischemia/Reperfusion and Time of Day / David J. Durgan and Martin E. Young -- Phosphotransfer Reactions in the Failing Heart / Joanne S. Ingwall -- Mitochondria in Cardiac Disease / Roberta A. Gottlieb, GioVanni Quarato and E. Dale Abel -- PPAR/PGC-1 Regulation of Metabolism in Cardiac Disease / Jennifer G. Duncan and Brian N. Finck -- AMPK and Metabolic Remodeling in Cardiac Disease / Thomas Pulinilkunnil, Jeevan Nagendran and Jason R.B. Dyck -- Mechanotransduction in Cardiac Hypertrophy and Ischemia / Miensheng Chu, Yevgeniya E. Koshman and Allen M. Samarel -- Cardiac Plasticity in Health and Disease / Raj B. Gondalia, Beverly A. Rothermel, Sergio Lavandero, Thomas G. Gillette and Joseph A. Hill -- Ubiquitylation -- Dependent Signaling in Heart Disease / Monte S. Willis, Andrea Portbury, Sarah Ronnebaum, Makhosazane Zungu and W.H. Davin Townley-Tilson, et al. -- Mechanisms of Cardiac Dysfunction Associated with Cancer Therapeutics / Vishnu Chintalgattu and Aarif Y. Khakoo -- Molecular Basis of Cardiac Development and Congenital Heart Disease / Vidu Garg -- Cellular Therapy for the Infarcted Myocardium / S.C. Den Hartogh, J.P. Sluijter, P.A. Doevendans and L.W. Van Laake -- Novel Approaches to Deliver Molecular Therapeutics in Cardiac Disease Using Adeno-Associated Virus Vectors / Kleopatra Rapti, Roger J. Hajjar and Thomas Weber -- Novel Delivery of Molecular Therapeutics to the Heart Using Non-biologic Constructs (PPMO/Morpholino) in Muscular Dystrophy / Alastair Crisp, Aurélie Goyenvalle and Kay Elizabeth Davies -- Molecular Imaging of Cardiovascular Disease / Patricia K. Nguyen, Divya Nag and Joseph C. Wu
Summary Translational Cardiology: Molecular Basis of Cardiac Metabolism, Cardiac Remodeling, Translational Therapies and Imaging Techniques provides an up-to-date introduction to the role circadian rhythms, cardiac plasticity, and mechanotransduction play in the heart, while at the same time introducing new developments in cellular, viral, and non-biologic therapies that are in the process of being developed. Importantly, the focus of this book is on topics that, due to their novelty, are largely not covered in the other major textbooks. A special emphasis is placed on the molecular basis of cardiac metabolism, new concepts in cardiac remodeling, and translational therapies and imaging techniques currently under development for clinical use. The chapters are written by experts from diverse clinical and biomedical research backgrounds. Translational Cardiology: Molecular Basis of Cardiac Metabolism, Cardiac Remodeling, Translational Therapies and Imaging Techniques simplifies the complexity of the molecular basis of disease by focusing on patient-oriented disease mechanisms and therapies and is of great value to a broad audience including physicians (e.g. cardiologists, cardiovascular surgeons, pathologists) as well as translational biomedical researchers in a wide range of disciplines
Analysis Medicine
Medicine & Public Health
Molecular Medicine
public health
Medicine (General)
Geneeskunde (algemeen)
Bibliography Includes bibliographical references and index
Subject Cardiology.
Heart -- Molecular aspects.
Heart Diseases -- therapy
Molecular Targeted Therapy
Myocardium -- metabolism
Translational Research, Biomedical
HEALTH & FITNESS -- Diseases -- Heart.
MEDICAL -- Cardiology.
Heart -- Molecular aspects.
Form Electronic book
Author Patterson, Cam
Willis, Monte S
ISBN 9781617798917