Title Chordomas and chondrosarcomas of the skull base and spine / edited by Griffith R. Harsh IV, Francisco Vaz-Guimaraes

Edition Second edition Published London : Academic Press is an imprint of Elsevier, [2018] ©2018

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Description 1 online resource (xix, 463 pages) : color illustrations Contents Section I: Embryology, pathology and molecular biology. Embryology of the skull base and vertebral column -- Pathology of chordoma and chondrosarcoma of the axial skeleton -- Molecular drivers in chordoma -- Molecular drivers in chondrosarcoma -- Section II: Demographics, presentation and diagnosis. Demographics, presentation, and diagnosis -- Differential diagnosis of clival and spinal tumors -- Imaging cranial base chordoma and chondrosarcoma -- Imaging chordoma and chondrosarcoma of the vertebrae and sacrum -- Section III: Surgery of skull base tumors. Surgical anatomy of the skull base -- Skull base tumors: surgical considerations -- Midline subfrontal approaches: the transbasal approach and extended modifications to access the clivus -- The endoscopic endonasal approach (EEA) to chordomas and chondrosarcomas -- Transoral approaches to midline skull base tumors -- Chordomas and chondrosarcomas of the skull base: anterolateral approaches -- Lateral approaches -- Subtemporal preauricular approach to the infratemporal fossa -- Chordomas and chondrosarcomas of the skull base: transpetrosal approaches -- Chordomas and chondrosarcomas of the skull base: retrosigmoid approaches -- The extreme lateral approach for chordomas and chondrosarcomas of the craniovertebral junction -- Staged approaches for large skull base chordomas and chondrosarcomas -- Cerebral revascularization for skull base tumors -- Skull base reconstruction following resection of skull base chordomas and chondrosarcomas -- Stabilization of the craniocervical junction following resection of chordomas and chondrosarcomas of the skull base -- Section IV: Surgery of spinal and sacral tumors. Chordomas and chondrosarcomas of the spine: pre-operative planning, surgical strategies and complications avoidance -- Surgical management of chordomas and chondrosarcomas of the cervical spine -- Surgical management of the chordomas and chondrosarcomas of the thoracic spine -- Surgical management of chordomas and chondrosarcomas of the lumbar spine -- Anatomical considerations for resection of chordomas and chondrosarcoma of the sacrum -- Surgical management of sacral chordoma -- Section V: Radiation therapy of chordomas and chondrosarcomas -- Fractionated photon radiation therapy for skull base chordomas and chondrosarcomas -- Stereotactic radiosurgery for skull base chordomas -- Proton therapy for skull base chordomas and chondrosarcomas -- Photon irradiation for spinal chordomas and chondrosarcomas -- Proton therapy for spinal chordomas and chondrosarcomas -- Heavy ion radiation for chordomas and chondrosarcomas -- Section VI: Special considerations -- Chordomas and chondrosarcomas in children -- Recurrent skull base chordomas: role of surgery -- Systemic therapies for locally recurrent or metastatic disease -- Chordomas and chondrosarcomas of the axial skeleton: emerging therapies and future directions -- Section vii: patient directory -- Prognosis, survival and surveillance -- The chordoma foundation -- Sarcoma patient advocacy: hope and help Summary "Chordomas and Chondrosarcomas of the Skull Base and Spine, Second Edition, is a major reference and guide for neurosurgeons, medical oncologists, neuroscientists, orthopedic surgeons, head and neck surgeons and radiation oncologists that treat patients and research chordomas and chondrosarcomas of the axial skeleton. This book is the unique result of the collaboration of multidisciplinary specialists from a wide variety of fields (neurological sciences, medical oncology, molecular biology, orthopedics and radiation oncology), offering the most relevant information about chordomas and chondrosarcomas of the axial skeleton from each of these fields condensed into one single volume. It contains new medical knowledge and scientific advances regarding the treatment of these types of tumors. Additionally, the book includes chapters written by the Chordoma Foundation and Sarcoma Foundation of America, providing the most valuable information and support for patients and their relatives"--Publisher's description Bibliography Includes bibliographical references and index Notes Online resource; title from electronic title page (ScienceDirect, viewed March 23, 2018) Subject Spine -- Cancer. Skull base -- Cancer Chordoma. Skull Base Neoplasms Chondrosarcoma Chordoma Spinal Neoplasms HEALTH & FITNESS -- Diseases -- General. MEDICAL -- Clinical Medicine. MEDICAL -- Diseases. MEDICAL -- Evidence-Based Medicine. MEDICAL -- Internal Medicine. Chordoma Skull base -- Cancer Spine -- Cancer Form Electronic book Author Harsh, Griffith R., IV, editor Vaz-Guimaraes, Francisco, editor. ISBN 9780128043332 0128043334

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