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Title Journey from cognition to brain to gene : perspectives from Williams syndrome / [edited by] Ursula Bellugi and Marie St. George
Published Cambridge, Mass. : MIT Press, ©2001
©2001

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Description 1 online resource (xx, 189 pages) : illustrations
Contents 1. The neurocognitive profile of Williams syndrome : a complex pattern of strengths and weaknesses / by Ursula Bellugi [and others] -- 2. Hypersociability : the social and affective phenotype of Williams syndrome / by Wendy Jones [and others] -- 3. Neurophysiological markers of face processing in Williams syndrome / by Debra L. Mills [and others] -- 4. Neuroanatomy of Williams syndrome : a high-resolution MRI study / by Allan L. Reiss [and others] -- 5. Cellular and molecular cortical neuroanatomy i Williams syndrome / by Albert M. Galaburda and Ursula Bellugi -- 6. Genome structure and cognitive map of Williams syndrome / by Julie R. Korenberg [and others]
Summary A blueprint for the investigation of neurodevelopmental disorders, this book presents the work of a team of scientists using a multidisciplinary, integrated approach to link genes with human behavior. Using Williams syndrome as a model, leading researchers in neuroanatomy, neurocognition, neurophysiology, and molecular genetics have built bridges between disciplines to link higher cognitive functions, their underlying neurobiological bases, and their molecular genetic underpinnings. One of the book's many strengths is that the scientists from each discipline studied the same individuals with Williams syndrome. As the book shows, Williams syndrome is a fascinating disorder because of the "peaks and valleys" among cognitive domains: severe intellectual deficits but remarkably spared and effusive language; specific impairment in spatial construction but great strength in face processing and sociability. By capitalizing on these dissociations in higher cognitive functioning, the book provides a model for the study of brain-behavior relationships as well as for the mapping of brain and behavior phenotypes to the genome and beyond. Contributors Ralph Adolphs, Twyla Alvarez, Lawrence Appelbaum, Ursula Bellugi, Dennis Burian, Xiao-Ning Chen, Michael Chiles, Stephan Eliez, Albert Galaburda, Hanao Hirota, Wendy Jones, Julie Korenberg, Zona Lai, Liz Lichtenberger, Alan Lincoln, Rumiko Matsuoka, Debra Mills, Helen Neville, Judy Reilly, Allan Reiss, Bruce Roe, Marie St. George, J. Eric Schmidtt, Erica Straus
Analysis NEUROSCIENCE/General
Bibliography Includes bibliographical references and index
Notes English
Print version record
Subject Williams syndrome -- Pathophysiology
Williams syndrome -- Genetic aspects
Cognition disorders in children.
Williams Syndrome -- genetics
Brain -- pathology
Cognition -- physiology
Williams Syndrome -- physiopathology
Williams Syndrome -- psychology
MEDICAL -- Pediatrics.
HEALTH & FITNESS -- Children's Health.
Cognition disorders in children
Form Electronic book
Author Bellugi, Ursula, 1931-2022
St. George, Marie.
LC no. 00054892
ISBN 9780262287395
0262287390
0262523124
9780262523127
1423726081
9781423726081