| Description |
1 online resource (1551 pages) : illustrations |
| Contents |
Metal-Catalyzed Cross-Coupling Reactions and More; Contents to Volume 1; Preface; List of Contributors; Chapter 1 Mechanistic Aspects of Metal-Catalyzed C, C- and C, X-Bond Forming Reactions; 1.1 Mechanisms of Cross-Coupling Reactions; 1.1.1 The Earlier Mechanistic Proposal: The Stille Reaction; 1.1.2 The Oxidative Addition; 1.1.2.1 Cis-Complexes in the Oxidative Addition; 1.1.2.2 The Role of Alkene and Anionic Ligands; 1.1.2.3 Cross-Couplings in the Presence of Bulky Phosphines; 1.1.2.4 N-Heterocyclic Carbenes as Ligands; 1.1.2.5 Palladacycles as Catalysts |
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1.1.2.6 Involvement of Pd(IV) in Catalytic Cycles1.1.2.7 Oxidative Addition of Stannanes to Pd(0); 1.1.3 The Transmetallation in the Stille Reaction; 1.1.3.1 Isolation of the Transmetallation Step; 1.1.3.2 Dissociative Mechanistic Proposals; 1.1.3.3 Cyclic and Open Associative Transmetallation; 1.1.3.4 The Copper Effect; 1.1.3.5 Transmetallation in the Suzuki-Miyaura Reaction; 1.1.3.6 Transmetallation in the Negishi Reaction; 1.1.3.7 Transmetallation in the Hiyama Reaction; 1.1.3.8 Couplings Catalyzed by Copper and Gold; 1.1.3.9 Couplings Catalyzed by Iron and Cobalt |
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1.1.4 Reductive Elimination1.2 Palladium-Catalyzed [alpha]-Arylation of Carbonyl Compounds and Nitriles; 1.3 Formation of C-X (X = N, O, S) Bonds in Metal-Catalyzed Reactions; 1.3.1 Reductive Elimination to Generate C-N, C-O, and C-S Bonds from Organopalladium(II) Complexes; 1.3.2 Nickel- and Copper-Catalyzed Formation of C-X Bonds; 1.4 Summary and Outlook; List of Abbreviations; References; Chapter 2 State-of-the-Art in Metal-Catalyzed Cross-Coupling Reactions of Organoboron Compounds with Organic Electrophiles; 2.1 Introduction; 2.1.1 Catalytic Cycle |
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2.1.2 Improvements toward More Efficient Cross-Coupling Conditions2.1.2.1 Development of New Phosphine and NHC Ligands; 2.1.2.2 Usage of Masked Boron Derivatives as Cross-Coupling Partners; 2.1.2.3 Lewis Acids as Additives; 2.1.2.4 Adjusting the Nucleophilicity of Organoboron Cross-Coupling Partners; 2.1.2.5 Copper Salts as Additives; 2.2 Advances in Cross-Coupling Reactions for the Formation of C(sp2)-C(sp2) Bonds; 2.2.1 Background; 2.2.2 Recent Developments in the Use of New Electrophilic Coupling Partners; 2.2.2.1 Chlorides; 2.2.2.2 Fluorides; 2.2.2.3 Pseudohalides |
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2.2.3 Recent Developments in Organoboron Cross-Coupling Partners2.2.3.1 Trifluoroborate Salts; 2.2.3.2 N-Methyliminodiacetic Acid (MIDA) Boronates; 2.2.3.3 Other Organoboron Cross-Coupling Partners; 2.2.4 Synthesis of Enantiomerically Enriched Atropisomers; 2.3 Advances in the Cross-Coupling Reactions for the Formation of C(sp3)-C(sp2) or C(sp3)-C(sp3) Bonds; 2.3.1 Background; 2.3.1.1 Stereochemistry; 2.3.2 Cross-Couplings between Unsaturated sp2 Carbon Centers and sp3 Carbon Centers; 2.3.2.1 Cross-Couplings between sp3 Alkyl Halides and sp2 Alkenyl or Aryl Boron Derivatives |
| Summary |
This is the follow-up handbook to the bestselling Metal-Catalyzed Cross Coupling Reactions, the definitive reference in the field. In line with the enormous developments in this area, this is not so much a new edition, but rather a new book in three volumes with over 50% more content. This new content includes C-H activation, shifting the focus away from typical cross-coupling reactions, while those topics and chapters found in Diederich/de Meijere's book have been updated and expanded. With its highly experienced editor team and the authors reading like an international Who's-Who in |
| Bibliography |
Includes bibliographical references at the end of each chapters and index |
| Notes |
Online resource; title from PDF title page (ebrary, viewed December 11, 2013) |
| Subject |
Organic compounds -- Synthesis.
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Metal catalysts.
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TECHNOLOGY & ENGINEERING -- Engineering (General)
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TECHNOLOGY & ENGINEERING -- Reference.
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Metal catalysts
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Organic compounds -- Synthesis
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| Form |
Electronic book
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| Author |
Meijere, A. de
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Bräse, Stefan
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Oestreich, Martin
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| ISBN |
9783527655618 |
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3527655611 |
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9783527655601 |
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3527655603 |
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9783527655595 |
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352765559X |
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9783527655588 |
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3527655581 |
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