| Description |
1 online resource (xv, 266 pages) : illustrations |
| Contents |
1. The history of twin and sibling-pair studies / Tim D. Spector -- 2. Influence of design on the outcome of twin studies / David P. Strachan -- 3. Sample selection and outcome definition in twin studies: experiences from the Finnish twin cohort study / Jaakko Kaprio, Pia K. Verkasalo and Markku Koskenvuo -- 4. Practical approaches to account for bias and confounding in twin data / Alex J. MacGregor -- 5. The co-twin control study / David L. Duffy -- 6. Generalisability and assumptions of twin studies / Kirsten Ohm Kyvik -- 7. Fetal programming or genes? / David W. Phillips -- 8. Twin and sib-pair studies in developing countries / Xiping Xu, Changzhong Chen and Tianhua Niu / [and others] -- 9. Comparison of analysis of variance and likelihood models of twin data analysis / Joe C. Christian and Christopher J. Williams -- 10. Path analysis of age-related disease traits / Harold Snieder -- 11. Survival analysis methods in twin research / Andrew Pickles -- 12. Gene-environment interaction and twin studies / Nick Martin -- 13. Why 'common environmental effects' are so uncommon in the literature / John L. Hopper -- 14. Using sib-pairs and parent-child trios in association studies / Cathryn M. Lewis -- 15. The concept of genome-wide power and a consideration of its potential use in mapping polygenic traits: the example of sib-pairs / David B. Allison and Myles S. Faith -- 16. The use of twins in quantitative trait locus mapping / Nicholas J. Schork and Xiping Xu -- 17. Multivariate QTL analysis using structural equation modelling: a look at power under simple conditions / Dorret I. Boomsma and Conor V. Dolan -- 18. QTL mapping with sib-pairs: the flexibility of Mx / Michael C. Neale -- 19. Implications of pharmacogenetic polymorphisms for human health / C. Roland Wolf and Gillian Smith |
| Bibliography |
Includes bibliographical references and index |
| Notes |
English |
|
Print version record |
| Subject |
Medical genetics -- Statistical methods
|
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Twins -- Research -- Methodology
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Siblings -- Research -- Methodology
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Genetics, Medical -- methods
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Twin Studies
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Twins -- genetics
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Diseases in Twins -- genetics
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HEALTH & FITNESS -- Diseases -- Genetic.
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MEDICAL -- Genetics.
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Medical genetics -- Statistical methods
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| Form |
Electronic book
|
| Author |
Snieder, Harold.
|
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MacGregor, Alex J.
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Spector, T. D. (Timothy David)
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| ISBN |
051104299X |
|
9780511042997 |
|
0585259321 |
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9780585259321 |
|
