Chemogenomics in drug discovery / H. Kubinyi -- Chemogenomics strategies for G-protein coupled receptor hit finding / W. Guba -- Chemogenomics approaches for G-protein coupled receptor lead finding / T. Klabunde, R. Jäger -- Diversity oriented synthesis: a challenge for synthetic chemists / A. Bender [and others] -- Probing protein function with small molecules / J.D. Gough, C.M. Crews -- Tamoxifen-based probes for the study of estrogen receptor-mediated transcription / J.P. Trebley [and others] -- Protein structure similarity clustering and natural product structure as guiding principles for chemical genomics / M.A. Koch, H. Waldmann -- Tackling the chemogenomic space by novel screening technologies / L.M. Mayr
Summary
Chemical genomics is a field of research both in academics and in the life sciences industry. Various aspects of the interface between chemistry and biology are covered in this volume, such as chemogenomics efforts in the pharmaceutical industry, diversity-oriented synthesis, chemogenomic approaches to the study of cell function, and more