Essential hypertension: a brief history -- What is high blood pressure? -- Epidemiology of hypertension -- Pathophysiology of essential hypertension -- High blood pressure (and the sympathetic nervous system) as a predictor of premature death and cardiovascular events -- Ways to lower blood pressure -- End-organ damage in essential hypertension -- Hard endpoint studies -- Hypertension and the heart rate factor -- The UK, European, and US guidelines regarding the treatment of essential hypertension