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Title 100 YEARS OF HUMAN CHORIONIC GONADOTROPIN : reviews and new perspectives
Published [S.l.] : ELSEVIER, 2020
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Description 1 online resource
Contents <P>Forward- 100 Years of hCG Introduction -- 100 Years of hCG -- Meet the Editors and the Authors Section 1 -- Genes and Structure Chapter 1.1 -- Isolating C5 and B152 -- Anecdote Chapter 1.2 -- Evolutionary, structural and physiological differences between hCG and LH Chapter 1.3 -- hCG and Human Evolution -- The Master Molecule Chapter 1.4 -- Human Chorionic Gonadotropin: Different Origins, Glycoforms and Functions during Pregnancy Chapter 1.5 -- Molecular Modelling of hCG: influence of glycosylation and nicking on molecular folding and epitope recognition Chapter 1.6 -- Why is hCG Glycosylated Section 2 -- Detection and Quantitation Chapter 2.1 -- Detecting hCG that's not there -- Annecdote Chapter 2.2 -- Quantification of hCG by MALDI ToF Mass Spectrometry Chapter 2.3 -- Pregnancy failures and false positive hCG tests Chapter 2.4 -- Home Pregnancy Tests Chapter 2.5 -- Human Chorionic Gonadotropin determination using mass spectrometry Chapter 2.6 -- Beta core fragment as a standard quality control in MALDI Section 3 -- Pregnancy and Fertility Chapter 3.1 -- hCG as an LH analogue -- Anecdote Chapter 3.2 -- The role of hCG in endometrial receptivity and embryo implantation Chapter 3.3 -- Qualitative Analysis of hCG Variants and Glycoforms in Urine Chapter 3.4 -- Phenotypic characterization of a transgenic mouse model overproducing hCG Chapter 3.5 -- The Role of Human Chorionic Gonadotropin in Reproductive Medicine Chapter 3.6 -- Pregnancy and hCG Chapter 3.7 -- My Journey with Human Chorionic Gonadotropin: development of a Unique Vaccine for control of fertility Chapter 3.8 -- Evaluation of Delivery Vectors for Active Immunisation with Synthetic Peptides of hCG as a Fertility Control Method Section 4 -- Cancer and Therapy Chapter 4.1 -- How hCG and a failed experiment changed my life -- Anecdote Chapter 4.2 -- Human chorionic gonadotropin in cancer -- where are we? Chapter 4.3 -- LH/hCG-receptor independent activities of hCG and hCGß Chapter 4.4 -- The Role of the Free Beta Subunit of Human Chorionic Gonadotropin in Human Malignancy Chapter 4.5 -- hCG and Gestational Trophoblastic Diseases -- Hydatidiform Mole and Choriocarcinoma Chapter 4.6 -- Immunotherapy of Advanced Stage, Invariably Drug Resistant Cancer Expressing ectopically hCG Chapter 4.7 -- A Potential Cure for Cancer Section 5 -- Conclusion Chapter 5.1 -- Where has hCG research been? What is hCG research doing? Which direction will it go in the future?</p>
Subject Chorionic gonadotropins.
Form Electronic book
ISBN 0128216093