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Author Kiel, Johnathan L., author

Title Type-B Cytochromes : Sensors and Switches / Jonathan L. Kiel
Published Boca Raton, FL : CRC Press, 2018


Description 1 online resource
Series CRC revivals
CRC revivals
Contents Cover; Half Title; Title Page; Copyright Page; PREFACE; THE AUTHOR; Table of Contents; Dedication; ACKNOWLEDGMENTS; Chapter 1: General Properties of a Primordial Cellular Sensor and Switch; Chapter 2: Primitive Type-B Cytochromes: Green Hemoproteins; Chapter 3: NADPH Oxidase and its Terminal Cytochrome; Chapter 4: Nitric Oxide Synthase; Chapter 5: Extracellular Disulfide Reductase; Chapter 6: Nitrogen Oxide Reductases; Chapter 7: Summary Schematics; Chapter 8: Future Research and Applications; References; Index
Summary This book describes cellular level sensors that act as switches, turning on gene expression and other metabolic processes necessary for cell survival and differentiation. These responses can also initiate programmed cell death or activate latent human immunodeficiency virus or animal leukemia viruses. These redox sensors are nonspecific in sensitivity but specific in response. Unlike ligand/antiligand-type specific sensors, they respond to ionizing and ultraviolet radiations, pH gradients, heat, light, electric and magnetic fields, redox chemicals, mechanical stress, and other nonspecific stressors. The sensors are type-b cytochromes, including NADPH oxidases, NO synthases, and nitrogen oxide reductases. The intense radiation of early pre-biotic earth may have been the evolutionary driving force for the development of their common ancestor
Bibliography Includes bibliographical references and index
Notes Vendor-supplied metadata
Subject Cytochrome b.
Cellular signal transduction.
Cell metabolism.
Cytochrome b Group
Signal Transduction
SCIENCE -- Life Sciences -- Biology.
Cell metabolism.
Cellular signal transduction.
Cytochrome b.
Form Electronic book
ISBN 9781351094313