Cover; Contents; Foreword from the First Edition; Preface to the First Edition; Preface to the Second Edition; PART ONE: The Brain, the Mind, and White Matter; 1. The Neurologic Background; White Matter in the History of Neurology; The Concept of Subcortical Dementia; White Matter and Higher Function; The Perspective of Behavioral Neurology; 2. White Matter Structure and Function; Neuroanatomy; Neurophysiology; 3. Neuroimaging; Computed Tomography; Magnetic Resonance Imaging; Magnetic Resonance Spectroscopy; Magnetization Transfer Imaging; Diffusion Tensor Imaging; Functional Neuroimaging
Mapping Neural Networks4. Development and Aging; Development of White Matter; White Matter Changes in Aging; PART TWO: Disorders of White Matter; 5. Genetic Disorders; Leukodystrophies; Fragile X Tremor/Ataxia Syndrome; Aminoacidurias; Phakomatoses; Mucopolysaccharidoses; Muscular Dystrophy; Callosal Agenesis; 6. Demyelinative Diseases; Multiple Sclerosis; Neuromyelitis Optica; Acute Disseminated Encephalomyelitis; Schilder's Disease; Marburg's Disease; Balò's Concentric Sclerosis; Tumefactive Multiple Sclerosis; 7. Infectious Diseases; Human Immunodeficiency Virus Infection
Progressive Multifocal LeukoencephalopathySubacute Sclerosing Panencephalitis; Progressive Rubella Panencephalitis; Varicella Zoster Vasculopathy; Cytomegalovirus Encephalitis; Lyme Encephalopathy; 8. Inflammatory Diseases; Systemic Lupus Erythematosus; Behçet's Disease; Sjögren's Syndrome; Wegener's Granulomatosis; Temporal Arteritis; Polyarteritis Nodosa; Scleroderma; Primary Angiitis of the Central Nervous System; Sarcoidosis; 9. Toxic Leukoencephalopathy; Radiation; Therapeutic Drugs; Drugs of Abuse; Environmental Toxins; The Spectrum of Toxic Leukoencephalopathy; 10. Metabolic Disorders
Cobalamin DeficiencyFolate Deficiency; Central Pontine Myelinolysis; Hypoxia; Hypertensive Encephalopathy; Eclampsia; High-Altitude Cerebral Edema; 11. Vascular Diseases; Binswanger's Disease; Leukoaraiosis; Cerebral Amyloid Angiopathy; CADASIL; Migraine; White Matter Disease of Prematurity; 12. Traumatic Disorders; Traumatic Brain Injury; Shaken Baby Syndrome; Corpus Callosotomy; Frontal Lobotomy; 13. Neoplasms; Gliomas; Gliomatosis Cerebri; Primary Central Nervous System Lymphoma; Focal White Matter Tumors; 14. Hydrocephalus; Early Hydrocephalus; Hydrocephalus Ex Vacuo
Normal Pressure HydrocephalusPART THREE: White Matter and Higher Function; 15. Cognitive Dysfunction and Dementia; Cognitive Dysfunction; White Matter Dementia; Why Another Dementia Syndrome?; 16. White Matter and Neurodegenerative Disease; Alzheimer's Disease; Frontotemporal Dementia; Parkinson's Disease; Dementia with Lewy Bodies; Huntington's Disease; Corticobasal Degeneration; Progressive Supranuclear Palsy; 17. Focal Neurobehavioral Syndromes; Amnesia; Aphasia; Apraxia; Alexia; Developmental Dyslexia; Gerstmann's Syndrome; Agnosia; Neglect; Visuospatial Dysfunction; Akinetic Mutism
Summary
Behavioral neurology is founded on lesions of cortical gray matter, but recently the contributions of cerebral white matter to cognitive and emotional dysfunction have also attracted attention. The Behavioral Neurology of White Matter surveys this broad and fascinating field from a clinical perspective. Stimulated by recent improvements in neuroimaging, white matter has been carefully studied, and its role in the operations of cognition and emotion clarified by correlations with clinical observations. The relevance of normal and abnormal white matter to behavioral neurology is apparent in ever
