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Book Cover
E-book
Author Staff, Institute of Medicine

Title Clinical Applications of Mifepristone (RU486) and Other Antiprogestins : Assessing the Science and Recommending a Research Agenda
Published Washington : National Academies Press, 1900

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Description 1 online resource (304 pages)
Contents ""Clinical Applications of Mifepristone (RU 486) and Other Antiprogestins""; ""Copyright""; ""Preface""; ""Contents""; ""Summary""; ""CROSS-CUTTING RECOMMENDATIONS""; ""USES OF ANTIPROGESTINS: THE REPRODUCTIVE CYCLE""; ""Contraception""; ""Post-Coital Contraception""; ""Menses Induction""; ""Pregnancy Termination During the First Trimester""; ""Pregnancy Termination During the Second Trimester""; ""Cervical Ripening""; ""Labor Induction in Late Pregnancy""; ""OTHER POTENTIAL THERAPEUTIC USES OF ANTIPROGESTINS""; ""Endometriosis""; ""Uterine Leiomyomas (Fibroids)""; ""Breast Cancer""
""Meningioma""""ANTIGLUCOCORTICOID EFFECTS OF ANTIPROGESTINS""; ""1 Introduction""; ""BACKGROUND AND HISTORICAL PERSPECTIVES""; ""Finding an Antiprogestin""; ""THE IOM REPORT""; ""CROSS-CUTTING RECOMMENDATIONS""; ""REFERENCES""; ""2 Uses of Antiprogestins: The Reproductive Cycle (Part I)""; ""CONTRACEPTION""; ""POST-COITAL CONTRACEPTION""; ""MENSES INDUCTION""; ""REFERENCES""; ""3 Uses of Antiprogestins: The Reproductive Cycle (Part II)""; ""PREGNANCY TERMINATION DURING THE FIRST TRIMESTER""; ""Health Services Research""; ""PREGNANCY TERMINATION DURING THE SECOND TRIMESTER""
""CERVICAL RIPENING""""LABOR INDUCTION IN LATE PREGNANCY""; ""Fetal Demise""; ""SUMMARY""; ""REFERENCES""; ""4 Other Therapeutic Uses of Antiprogestins""; ""ENDOMETRIOSIS""; ""Utility of Mifepristone (RU 486) for Treatment of Endometriosis""; ""Summary""; ""UTERINE LEIOMYOMAS (FIBROIDS)""; ""Utility of Mifepristone for Treatment of Uterine Leiomyomas""; ""BREAST CANCER""; ""Mechanism of Action""; ""Clinical Issues""; ""Adjuvant Therapy and Chemoprevention""; ""Resistance""; ""Dose Issues""; ""Conclusions""; ""MENINGIOMAS""; ""Conclusions""; ""REFERENCES""
""5 Antiglucocorticoid Effects of Antiprogestins""""GLUCOCORTICOID FUNCTION""; ""THERAPEUTIC USE OF MIFEPRISTONE (RU 486) AS ANANTIGLUCOCORTICOID""; ""ADVERSE ANTIGLUCOCORTICOID EFFECTS OF ANTIPROGESTINS""; ""REFERENCES""; ""6 Animals as Models for Studying Antiprogestins""; ""REFERENCES""; ""APPENDIXES""; ""A Agenda for the IOM Workshop ''Antiprogestins: Assessing the Science, "" April 13�14, 1993""; ""B Background Papers and Presentations (In Order of Presentation at IOM Workshop)""; ""B1 1993: RU 486�A DECADE ON TODAY AND TOMORROW""; ""ANTIHORMONES: THE 20 YEARS BEFORE RU 486""
""CHEMISTRY: NOVEL MOLECULES""""CELLULAR AND MOLECULAR MECHANISMS OF ACTION OF ANTIPROGESTINS: THE RECEPTOR AT THE CENTER""; ""Ligand Binding""; ""Receptor Transconformation""; ""Heat Shock Protein Binding""; ""Receptor Dimerization""; ""Binding to DNA""; ""Studies of Chromatin""; ""Gene Transcription""; ""PHYSIOPHARMACOLOGICAL REPRODUCTIVE EFFECTS""; ""REPRODUCTIVE MEDICINE (TABLE B1.4)""; ""Voluntary Early Pregnancy Interruption""; ""Pregnancy Interruption After Nine Weeks of Amenorrhea""; ""Initiation of Labor""; ""Contragestive and Contraceptive Methods Using RU 486""
Notes ""Emergency Post-Coital Contraception (Contraceptive or Contragestive According to When it is Applied)""
Print version record
Subject Mifepristone -- Research
Abortifacients -- Research
Progesterone -- Antagonists -- Research
Form Electronic book
Author Donaldson, Molla S
Dorflinger, Laneta
ISBN 9780309598354
0309598354