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Title Aerobiology : the toxicology of airborne pathogens and toxins / editors: Harry Salem, Sidney A. Katz, Tim Marrs, Diana Anderson
Published [Cambridge] : Royal Society of Chemistry, 2016
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Description 1 online resource
Series Issues in toxicology ; 25
Issues in toxicology ; 25
Contents Cover; Aerobiology The Toxicology of Airborne Pathogens and Toxins; Preface; Acknowledgements; Contents; Chapter 1 -- The Atmosphere: Its Developmental History and Contributions to Microbial Evolution and Habitat†; Chapter 2 -- Orthopoxviruses and Animal Models for Pathogenesis, Vaccine and Drug Studies†; Chapter 3 -- Inhalational Anthrax -- Issues in Dose-Response and Hazard Evaluation; Chapter 4 -- Toxicity of Botulinum Neurotoxin by Inhalation: Implications in Bioterrorism†
3.2 Problem Characterization3.3 Inhalational Anthrax -- Pathogenesis and Treatment; 3.4 Physical and Biological Factors Affecting Inhalational Risk; 3.5 Overview of Dose-Response Regression Models; 3.6 Dose-Response Studies and Modeling in Animals; 3.7 The Sverdlovsk Accidental Release and Incubation Period Modeling; 3.8 The 1957 Goat Hair Mill Outbreak and Its Implications -- "From Mills to Mail"; 3.9 Evaluation, Conclusions and Future Directions; 3.10 Summary; References; 4.1 Introduction; 4.2 BoNT As a Biowarfare and Bioterrorist Threat; 4.3 Potency of BoNT by Inhalation
4.4 Mechanism of Entry of Aerosolized BoNT4.5 Human Case Reports of Inhalation Botulism; 4.6 Histopathological Alterations Following BoNT Exposure; 4.7 Detection and Diagnosis; 4.8 Medical Countermeasures for Inhalation Botulism; 4.9 Summary and Conclusions; Abbreviations; Acknowledgements; References; 5.1 Introduction; 5.2 Structural Biology and Biochemistry of the Ricin Ribosome Inactivating Protein; 5.3 Weaponization of the Ricin Toxin; 5.4 Inhalation of Aerosolized Ricin; 5.5 Signs, Symptoms and Toxicity of Ricin Exposure; 5.6 Conclusions; Acknowledgements; References; 6.1 Introduction
Chapter 13 -- Aerosol Exposure to Pathogenic Bacteria and Virus Particles: Standard Operating ProcedureChapter 14 -- Programming an Agent-Based Model for Disease Dynamics with Multiple Sources of Infection†; Subject Index; 1.1 Introduction; 1.2 The Origin and Evolution of the Earth's Atmosphere; 1.3 Evolutionary History of the Atmosphere; 1.4 Microbial Life in the Atmosphere; 1.5 Conclusion; Acknowledgements; References; 2.1 Introduction; 2.2 The Poxviruses; 2.3 Clinical Aspects of Poxvirus Infections; 2.4 Animal Models and Aerosol Studies; 2.5 Conclusion; References; 3.1 Introduction
Chapter 5 -- The Structural Biology and Biochemistry of the Ricin Toxin and the Military Use and Inhalation Toxicology of Ricin Aerosols†Chapter 6 -- Bioaerosols in the Environment: Populations, Measurement and Processes; Chapter 7 -- Bacillus anthracis: An Aerobiological Threat†; Chapter 8 -- Detection of Airborne Pathogens and Toxins; Chapter 9 -- Aerobiological Aspects of Biological Warfare†; Chapter 10 -- Aerosol Physics for Bioaerosols†; Chapter 11 -- Respiratory Protection Against Some Pathogens and Toxins; Chapter 12 -- An Improved Model of Human Response to Bioaerosol Exposure
Summary Aerobiology is the study of airborne organic particulates in the environment, such as bacteria or fungal spores. These can be either naturally occurring or artificially introduced into the air. Some of the toxicological, pharmacological, and physiological effects of bioaerosols include infections, allergies, and cancer. Research efforts in aerobiology range from remediating household mould to combating bioterrorism. This book focusses on the toxicological aspects of aerobiology, considering the adverse health effects associated with the inhalation of specific bioaerosols, such as anthrax and ricin. Additionally, chapters cover techniques for generating, sampling and characterizing airborne biological materials as well as methods for establishing standards of exposure. Moreover, mitigation of exposure and protection against exposure are described. Bringing together the contemporary status of information in the area, this book will be a valuable reference book for pulmonary specialists, general practitioners of medicine, public health and public safety officers, first responders, military personnel, and students studying toxicology and related disciplines
Notes Online resource; title from PDF title page (Royal Society of Chemistry, viewed May 10, 2016)
Subject Air -- Microbiology.
Upper atmosphere -- Microbiology.
Form Electronic book
Author Anderson, Diana, editor
Katz, Sidney A., 1935- editor
Marrs, Timothy C., editor
Salem, Harry, 1929- editor
Royal Society of Chemistry (Great Britain)
ISBN 1849737916 (electronic bk.)
9781849737913 (electronic bk.)