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Title Developmental immunotoxicology / edited by Steven D. Holladay
Published Boca Raton : CRC Press, ©2005


Description 1 online resource (364 pages) : illustrations
Contents Chapter Introduction -- chapter The Editor -- chapter Contributors -- chapter Contents -- chapter PART I Development of the Immune System -- chapter 1 Development of the Rodent Immune System -- chapter 2 Development of the Human Immune System -- chapter PART II Developmental Immunotoxicology: Models -- chapter 3 Risk Assessment Perspectives for Developmental Immunotoxicity -- chapter 4 The Mouse as a Model for Developmental Immunotoxicology / M. Renee Prater -- chapter 5 The Rat as a Model for Developmental Immunotoxicology / Ralph J. Smialowicz -- chapter 6 The Pig as a Model for Developmental Immunotoxicology / Hermann J. Rothkötter -- chapter 7 The Nonhuman Primate as a Model of Developmental Immunotoxicity / Andrew G. Hendrickx -- chapter PART III Developmental Immunotoxicant Exposure and Postnatal Immunosuppression -- chapter 8 Developmental Immunotoxicity of Halogenated Aromatic Hydrocarbons and Polycyclic Aromatic Hydrocarbons / Terry C. Hrubec -- chapter 9 Developmental Immunotoxicity of Chlordane / John B. Barnett -- chapter 10 Toxicity of Lead to the Developing Immune System / Rodney R. Dietert -- chapter 11 Developmental Immunotoxicity of Therapeutic Immunosuppressive Drugs / Robert M. Gogal, Jr. and Steven D. Holladay -- chapter 12 Mycotoxins and Other Miscellaneous Developmental Immunotoxicants / Terry C. Hrubec -- chapter PART IV Developmental Immunotoxicant Exposure and Exacerbated Postnatal Immune Responses -- chapter 13 Perinatal Immunotoxicant Exposure and Autoimmune Disease / Benny L. Blaylock -- chapter 14 Developmental Immunotoxicant Exposure and Exacerbated Postnatal Immune Responses: Asthma / John M. Armstrong -- chapter PART V Neuroimmune Interactions -- chapter 15 Developmental Neurotoxicity and Postnatal Immune Deficits / Patricia V. Basta -- chapter 16 Neuroendocrine-Immune Interactions: Impact of Gender, Negative Energetic Balance Condition, and Developmental Stage on the Mechanisms of the Acute Phase Response of the Inflammatory Process in Mammals
Summary Despite rapidly increasing interest in developmental immunotoxicology, there is not yet a textbook focused on this hot area of research. Developmental Immunotoxicology fills the void with overviews of immune system development in experimental animal and human models, and discusses the complex issues related to the evolution of developmental immunology and risk assessment. This text describes different models used to study developmental immunotoxicology and examples of specific developmental immunotoxic agents, including therapeutics. The text concludes with several chapters that describe the role of neuroimmune interactions as they relate to developmental immunotoxicology.Using a didactic approach, Developmental Immunotoxicology provides an explanatory overview of this cutting-edge field for toxicologists, immunologists, and developmental biologists. It provides a lucid account of this area of research-proposing answers to some questions and stimulating debate on those questions yet to be addressed by the research community
Bibliography Includes bibliographical references and index
Notes Print version record
Subject Immunotoxicology.
Developmental toxicology.
Newborn infants.
Human beings.
Infant, Newborn
Immunotoxins -- adverse effects
Immune System -- growth & development
Prenatal Exposure Delayed Effects
Homo sapiens (species)
MEDICAL -- Immunology.
HEALTH & FITNESS -- Allergies.
HEALTH & FITNESS -- Diseases -- Immune System.
MEDICAL / Immunology
MEDICAL / Toxicology
SCIENCE / Life Sciences / Biology / Developmental Biology
Newborn infants
Developmental toxicology
Postnatale ontwikkeling.
Form Electronic book
Author Holladay, Steven D.
LC no. 2004054496
ISBN 1420024035