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Book Cover
Author Chin, Richard.

Title Adaptive and flexible clinical trials / Richard Chin
Published Boca Raton, Fla. : CRC Press, 2012
Online access available from:
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Description 1 online resource (xiii, 184 pages) : illustrations
Contents 1. Background -- 2. Conventional statistics -- 3. Statistics used in adaptive clinical trials -- 4. Specific requirements for adaptive trials -- 5. Adaptive randomization and allocation -- 6. Sample size reestimation -- 7. Traditional dosing -- 8. Adaptive dosing -- 9. Interim analysis and adaptive termination of study and study arms -- 10. Adaptive changes in study design and decision rules -- 11. Seamless designs and adaptive clinical trial conduct -- 12. Analysis and interpretation of results
Notes "A Chapman & Hall book."
Bibliography Includes bibliographical references and index
Subject Clinical trials.
Clinical Trials as Topic.
Database Management Systems -- trends.
Efficiency, Organizational.
Research Design.
Form Electronic book
ISBN 143983833X (electronic bk.)
9781439838334 (electronic bk.)
(alk. paper)